Results 181 to 190 of about 274,722 (228)
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Journal of Allergy and Clinical Immunology: In Practice
BACKGROUND The pivotal phase 3 EPITOPE trial, a 12-month, double-blind, placebo-controlled study of epicutaneous immunotherapy with the VIASKIN® patch containing 250 μg peanut protein (VP250) previously reported significant treatment response vs placebo ...
M. Greenhawt +60 more
semanticscholar +1 more source
BACKGROUND The pivotal phase 3 EPITOPE trial, a 12-month, double-blind, placebo-controlled study of epicutaneous immunotherapy with the VIASKIN® patch containing 250 μg peanut protein (VP250) previously reported significant treatment response vs placebo ...
M. Greenhawt +60 more
semanticscholar +1 more source
Epicutaneous Immunotherapy Using a New Epicutaneous Delivery System in Mice Sensitized to Peanuts
International Archives of Allergy and Immunology, 2010<i>Background:</i> Peanut allergy is a life-threatening condition for which new efficient and safe treatment is expected. We evaluated epicutaneous immunotherapy (EPIT) as a new alternative treatment for peanut allergy in sensitized mice. <i>Methods:</i> Sixty BALB/c mice were sensitized by gavages with peanut protein extract ...
Lucie, Mondoulet +5 more
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Carbohydrate Polymers
Peanut allergies are life-threatening conditions affecting millions of individuals globally, with severe allergic reactions, such as anaphylaxis, posing significant health risks. Despite advances in allergy treatment, an urgent need remains for safer and
Youseong Kim +7 more
semanticscholar +1 more source
Peanut allergies are life-threatening conditions affecting millions of individuals globally, with severe allergic reactions, such as anaphylaxis, posing significant health risks. Despite advances in allergy treatment, an urgent need remains for safer and
Youseong Kim +7 more
semanticscholar +1 more source
Epicutaneous immunotherapy for peanut allergy treatment in pediatrics: A literature review
Pediatric Sciences JournalPeanut allergy in children is a growing public health concern that significantly affects patients' quality of life. Although oral immunotherapy (OIT) has shown effectiveness in desensitizing allergic reactions, it is associated with a threefold increased
Vannisa Fadya +3 more
semanticscholar +1 more source
Current Treatment Options in Allergy, 2017
The current standard of care treatment for food allergy relies on avoidance. However, as outlined in this review, over the past decade, the literature has grown significantly showing promising results for interventional therapies for IgE-mediated food allergies utilizing oral immunotherapy (OIT), sublingual immunotherapy (SLIT), and epicutaneous ...
Tiffany J. Lieu, J. Andrew Bird
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The current standard of care treatment for food allergy relies on avoidance. However, as outlined in this review, over the past decade, the literature has grown significantly showing promising results for interventional therapies for IgE-mediated food allergies utilizing oral immunotherapy (OIT), sublingual immunotherapy (SLIT), and epicutaneous ...
Tiffany J. Lieu, J. Andrew Bird
openaire +1 more source
Epicutaneous/transcutaneous allergen-specific immunotherapy: rationale and clinical trials
Current Opinion in Allergy & Clinical Immunology, 2010IgE-mediated allergies, such as allergic rhinoconjunctivitis and asthma, have become highly prevalent, today affecting up to 35% of the population in industrialized countries. Allergen immunotherapy (also called hyposensitization therapy, desensitization or allergen-specific immunotherapy), the administration of gradually increasing amounts of an ...
Senti, G, Freiburghaus, A U, Kundig, T M
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Annals of Allergy, Asthma & Immunology
BACKGROUND There is a high prevalence rate of atopic comorbidities, including atopic dermatitis (AD), asthma, and concomitant food allergy (CFA), in children with peanut allergy. OBJECTIVE To evaluate whether concomitant atopic comorbidities affect the
A. Scurlock +14 more
semanticscholar +1 more source
BACKGROUND There is a high prevalence rate of atopic comorbidities, including atopic dermatitis (AD), asthma, and concomitant food allergy (CFA), in children with peanut allergy. OBJECTIVE To evaluate whether concomitant atopic comorbidities affect the
A. Scurlock +14 more
semanticscholar +1 more source
Epicutaneous Immunotherapy in Grass-Induced Allergic Rhinitis
Current Allergy and Asthma Reports, 2010As we approach the 100th anniversary of the first use of subcutaneous immunotherapy, a robust literature has demonstrated its efficacy in the treatment of allergic rhinitis and asthma, its ability to provide lasting efficacy following discontinuation, as well as its ability to potentially deter the allergic march. Despite these positive findings, it is
openaire +2 more sources
Advances in the management of peanut allergy (oral immunotherapy and epicutaneous immunotherapy)
Allergy and Asthma Proceedings, 2020Background: Peanut allergy affects up to 2% of the general population and carries not only the risk of potentially life-threatening allergic reactions but also negatively impacts day to day life for patients and their families. Advances in knowledge in immunotherapy is providing families with options for proactive treatment. Objective: To examine the
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Safety and efficacy of epicutaneous immunotherapy for food allergy
Pediatric Allergy and Immunology, 2018AbstractFood allergy is increasingly common in children, affecting about 4%‐8%. The mainstays of management remain allergen avoidance and emergency preparedness to treat allergic reactions with emergency medications. Unfortunately, these approaches are unsatisfactory for many patients and their families as the restrictions, constant vigilance, and ...
Julie Wang, Hugh A. Sampson
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