Results 1 to 10 of about 648,509 (314)

Prevalence and clinicopathological features of human epidermal growth factor receptor-2–low breast cancers: A single-center experience [PDF]

Journal of International Medical Research
Objective Human epidermal growth factor receptor-2–low breast cancer, characterized by low-level human epidermal growth factor receptor-2 expression and immunohistochemistry score 1+ or immunohistochemistry score 2+ without amplification, has been ...
ılkay Cinar
doaj   +2 more sources

Repurposed anti-cancer epidermal growth factor receptor inhibitors: mechanisms of neuroprotective effects in Alzheimer’s disease

Neural Regeneration Research, 2022
Numerous molecular mechanisms are being examined in an attempt to discover disease-modifying drugs to slow down the underlying neurodegeneration in Alzheimer’s disease.
Heba M Mansour, Hala M Fawzy, Aiman S El-Khatib, Mahmoud M Khattab   +3 more
doaj   +1 more source

An EGFR T790M-mutated lung adenocarcinoma undergoing large-cell neuroendocrine carcinoma transformation after osimertinib therapy: a case report

Journal of Medical Case Reports, 2020
Background Osimertinib, a third-generation epidermal growth factor receptor tyrosine kinase inhibitor, is selective for both epidermal growth factor receptor tyrosine kinase inhibitor–sensitizing and T790M resistance mutations.
Shinichi Miyazaki, Yasumasa Kuno, Shunsaku Hayai, Ryo Teramachi, Ryo Yamashita, Yusuke Saito, Kosuke Higuchi, Yoshiharu Nara, Takuya Ikeda   +8 more
doaj   +1 more source

Epidermal Growth Factor Receptor immunohistochemical expression in hepatocellular carcinoma without Epidermal Growth Factor Receptor exons 18–21 mutations

Romanian Journal of Internal Medicine, 2022
Introduction: EGFR targeted therapies, have been proved beneficial for patients with HCC, nevertheless additional research on EGFR immunoexpresion and EGFR mutations is still needed, especially in population in which it has not been done yet.
Nikolova Dafina, Trajkovska Meri, Trpcevska Emilija Nikolovska, Eftimov Aleksandar, Jovanovik Rubens, Janevska Vesna   +5 more
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Human Epidermal Growth Factor Improves Atopic Disease-like Skin Lesions in DFE/DNCB Induced BALB/c Mice and Human Keratinocytes [PDF]

운동과학, 2022
PURPOSE Atopic skin disease is an inflammatory disease with a multifactorial pathogenesis that presents as itchy, dry skin. Human epidermal growth factor (EGF) plays an essential role in regulating cell growth, proliferation, and differentiation ...
Nang-Kyu Kim, Sung-Hoon Kim, Bo-Hyeon Park, Eun-Ju Choi   +3 more
doaj   +1 more source

Epidermal growth factor receptor (EGFR) gene alteration and protein overexpression in Malaysian triple-negative breast cancer (TNBC) cohort [PDF]

, 2019
Background: Epidermal growth factor receptor (EGFR) is a member of the ErbB family of tyrosine kinase receptor proteins that plays important roles in tumour cell survival and proliferation.
Abdul Raub, Sayyidi Hamzi, Azhari, Azlah Kamilah, Eswaran, Jeyanthy, Soundararajan, Meera, Syed Husain, Sharifah Noor Akmal, Wan Hasan, Wan Atiqah Najiah, Zakaria, Zubaidah, Zulkifle, Muhamad Farid   +7 more
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Structure-Activity Relationship of Indole-Tethered Pyrimidine Derivatives that Concurrently Inhibit Epidermal Growth Factor Receptor and Other Angiokinases. [PDF]

PLoS ONE, 2015
Antiangiogenic agents have been widely investigated in combination with standard chemotherapy or targeted cancer agents for better management of advanced cancers.
Jiho Song, Jakyung Yoo, Ara Kwon, Doran Kim, Hong Khanh Nguyen, Bong-Yong Lee, Wonhee Suh, Kyung Hoon Min   +7 more
doaj   +1 more source

Effect on the canine Eck fistula liver of intraportal TGF‐β alone or with hepatic growth factors [PDF]

, 1992
Transforming growth factor‐β canceled the hepatocyte proliferation caused by transforming growth factor‐α when the two substances were mixed and administered through a disconnected central portal vein branch after creation of an Eck fistula. In contrast,
Alessandro Azzarone, Antonio Francavilla, Braun, Carlo Scotti-Fogueni, Carr, Fausto, Francavilla, Francavilla, Goustin, Gruppuso, Guiseppe Carrieri, Houck, Kendrick Porter, Mazzaferro, Mead, Michalopoulos, Michalopoulos, Qia-Hua Zeng, Richman, Roberts, Short, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Thomas E. Starzl, Umberto Cillo   +28 more
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Potential Role of EGF and EGFR in Tongue Coating Formation

World Journal of Traditional Chinese Medicine, 2016
Tongue coating, as a sensitive index of the physiological and pathological changes of human organs, is an important basis for the Traditional Chinese Medicine (TCM) syndrome differentiation and treatment.
Yi-Shuang Tang, Yu-Feng Mao, Yu Zhao, Jing-Hua Peng, Yi-Yang Hu   +4 more
doaj   +1 more source

Intraocular Metastases Secondary to Breast Carcinoma Correlates With Upregulation of Estrogen and Progesterone Receptor Expression in the Primary Tumor [PDF]

, 2016
To compare estrogen (ER), progesterone (PR), and human epidermal growth factor-2 (HER2) receptor expression in the primary tumor of patients affected by choroidal metastases from breast carcinoma (BC) versus those with extraocular ...
Frizziero, Luisa, Midena, Edoardo, Miglionico, Giacomo, Parrozzani, Raffaele, Perrini, Pierdavide, Pilotto, Elisabetta, Pulze, Serena, Testi, Ilaria   +7 more
core   +1 more source