Results 11 to 20 of about 1,962,623 (304)

Epidermal Growth Factor Receptor immunohistochemical expression in hepatocellular carcinoma without Epidermal Growth Factor Receptor exons 18–21 mutations

Romanian Journal of Internal Medicine, 2022
Introduction: EGFR targeted therapies, have been proved beneficial for patients with HCC, nevertheless additional research on EGFR immunoexpresion and EGFR mutations is still needed, especially in population in which it has not been done yet.
Nikolova Dafina, Trajkovska Meri, Trpcevska Emilija Nikolovska, Eftimov Aleksandar, Jovanovik Rubens, Janevska Vesna   +5 more
doaj   +1 more source

Human Epidermal Growth Factor Improves Atopic Disease-like Skin Lesions in DFE/DNCB Induced BALB/c Mice and Human Keratinocytes [PDF]

운동과학, 2022
PURPOSE Atopic skin disease is an inflammatory disease with a multifactorial pathogenesis that presents as itchy, dry skin. Human epidermal growth factor (EGF) plays an essential role in regulating cell growth, proliferation, and differentiation ...
Nang-Kyu Kim, Sung-Hoon Kim, Bo-Hyeon Park, Eun-Ju Choi   +3 more
doaj   +1 more source

Outcome of Epidermal Growth Factor Receptor Mutated and Non Mutated Adenocarcinoma Lung to Standard Therapy

Journal of Nepal Health Research Council, 2023
Background: Asian patients with adenocarcinoma of lung have higher incidence of epidermal growth factor receptor mutations which predict increased response and survival in patients to oral tyrosine kinase inhibitors.
Soniya Dulal, Akshat Mishra, Aarati Shah, Bibek Acharya, Ramila Shilpakar, Sandhya Chapagain Acharya, Ambuj Karn, Rajeev Sharma, Balram Gautam, Bishnu Dutta Paudel   +9 more
doaj   +1 more source

Epidermal Growth Factor

Annual Review of Biochemistry, 1979
During the course of purifying nerve growth factor from the submaxillary gland of the mouse, Cohen (1960) and Levi-Montalcini and Cohen (1960) noticed that daily injections of certain gland extract fractions into newborn mice produced developmental changes that could not be ascribed to nerve growth factor.
G, Carpenter, S, Cohen
openaire   +3 more sources

American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer.

Archives of Pathology & Laboratory Medicine, 2006
PURPOSE To develop a guideline to improve the accuracy of human epidermal growth factor receptor 2(HER2) testing in invasive breast cancer and its utility as a predictive marker.
Antonio C. Wolff, M. Hammond, Jared N. Schwartz, K. Hagerty, D. Allred, Richard J. Cote, M. Dowsett, P. Fitzgibbons, Wedad M. Hanna, A. Langer, L. McShane, S. Paik, M. Pegram, Edith A. Perez, Michael F. Press, A. Rhodes, C. Sturgeon, S. Taube, R. Tubbs, Gail H. Vance, Marc van de Vijver, Thomas M. Wheeler, Daniel F. Hayes   +22 more
semanticscholar   +1 more source

Potential Role of EGF and EGFR in Tongue Coating Formation

World Journal of Traditional Chinese Medicine, 2016
Tongue coating, as a sensitive index of the physiological and pathological changes of human organs, is an important basis for the Traditional Chinese Medicine (TCM) syndrome differentiation and treatment.
Yi-Shuang Tang, Yu-Feng Mao, Yu Zhao, Jing-Hua Peng, Yi-Yang Hu   +4 more
doaj   +1 more source

Structure-Activity Relationship of Indole-Tethered Pyrimidine Derivatives that Concurrently Inhibit Epidermal Growth Factor Receptor and Other Angiokinases. [PDF]

PLoS ONE, 2015
Antiangiogenic agents have been widely investigated in combination with standard chemotherapy or targeted cancer agents for better management of advanced cancers.
Jiho Song, Jakyung Yoo, Ara Kwon, Doran Kim, Hong Khanh Nguyen, Bong-Yong Lee, Wonhee Suh, Kyung Hoon Min   +7 more
doaj   +1 more source

Strategies for monitoring and combating resistance to combination kinase inhibitors for cancer therapy

Genome Medicine, 2017
Targeted therapies such as kinase inhibitors and monoclonal antibodies have dramatically altered cancer care in recent decades. Although these targeted therapies have improved patient outcomes in several cancer types, resistance ultimately develops to ...
Leanne G. Ahronian, Ryan B. Corcoran
doaj   +1 more source

Specific antibodies and sensitive immunoassays for the human epidermal growth factor receptors (HER2, HER3, and HER4)

Tumor Biology, 2017
The use of trastuzumab in patients with breast cancer that overexpresses human epidermal growth factor receptor 2 has significantly improved treatment outcomes.
Marianne Nordlund Broughton, Arne Westgaard, Elisabeth Paus, Miriam Øijordsbakken, Karoline J Henanger, Bjørn Naume, Trine Bjøro   +6 more
doaj   +1 more source

Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

Nature Medicine, 2016
Although mechanisms of acquired resistance of epidermal growth factor receptor (EGFR)-mutant non-small-cell lung cancers to EGFR inhibitors have been identified, little is known about how resistant clones evolve during drug therapy.
A. Hata, M. Niederst, Hannah L. Archibald, María Gomez-Caraballo, Faria M. Siddiqui, Hillary E. Mulvey, Y. Maruvka, Fei Ji, H. Bhang, Viveksagar Krishnamurthy Radhakrishna, G. Siravegna, Haichuan Hu, S. Raoof, Elizabeth Lockerman, Anuj Kalsy, Dana Lee, Celina Keating, D. Ruddy, Leah J. Damon, A. Crystal, C. Costa, Z. Piotrowska, A. Bardelli, A. Iafrate, R. Sadreyev, F. Stegmeier, G. Getz, L. Sequist, A. Faber, J. Engelman   +29 more
semanticscholar   +1 more source