Results 21 to 30 of about 410,903 (309)

Factors associated with efficacy of first-generation epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancer

Tumor Biology, 2017
The finding of epidermal growth factor receptor tyrosine kinase inhibitors, which reflects a classical process of translational research, is a critical milestone for non-small-cell lung cancer treatment.
Shaohua Cui, Liyan Jiang
doaj   +1 more source

Arctigenin induced gallbladder cancer senescence through modulating epidermal growth factor receptor pathway

Tumor Biology, 2017
Gallbladder cancer has poor prognosis and limited therapeutic options. Arctigenin, a representative dibenzylbutyrolactone lignan, occurs in a variety of plants.
Mingdi Zhang, Shizhong Cai, Bin Zuo, Wei Gong, Zhaohui Tang, Di Zhou, Mingzhe Weng, Yiyu Qin, Shouhua Wang, Jun Liu, Fei Ma, Zhiwei Quan   +11 more
doaj   +1 more source

Prevalence of Epidermal Growth Factor Receptor Mutations in Patients with Non-Small Cell Lung Cancer in Turkish Population

Balkan Medical Journal, 2017
Aims: Epidermal growth factor receptor mutation analysis in non-small cell lung cancer is important for selecting patients who will receive treatment with tyrosine kinase inhibitors.
Gaye Güler Tezel, Ebru Şener, Çisel Aydın, Sevgen Önder   +3 more
doaj   +1 more source

Differential activity of 2-methylene-19-nor vitamin D analogs on growth factor gene expression in rhino mouse skin and comparison to all-trans retinoic acid. [PDF]

PLoS ONE, 2017
While all 2-methylene-19-nor analogs of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3) tested produce an increase in epidermal thickness in the rhino mouse, only a subset reduce utricle size (comedolysis).
Jamie M Ahrens, James D Jones, Nirca J Nieves, Ann M Mitzey, Hector F DeLuca, Margaret Clagett-Dame   +5 more
doaj   +1 more source

The urine as a diagnostic key for a homozygous EGFR mutation [PDF]

Revista Portuguesa de Nefrologia e Hipertensão, 2022
Primary inherited epidermal growth factor receptor defects have recently been described in severe inflammatory skin disease and diarrhoea case reports. We describe two case reports of female preterm newborns of Roma consanguineous parents who presented ...
Mafalda Casinhas Santos, Margarida Almendra, Sofia Bota, Helena Ramos, Telma Francisco   +4 more
doaj   +1 more source

Transforming Growth Factor Alpha Stimulation of Mucosal Tissue Cultures from Head and Neck Squamous Cell Carcinoma Patients Increases Chemoresistance to Cisplatin [PDF]

, 2010
The monoclonal epidermal growth factor receptor ( EGFR) antibody cetuximab (Erbitux(TM)) was recently approved by the European Medicines Agency for the treatment of recurrent and/or metastatic head and neck squamous cell carcinoma (HNSCC) in combination ...
Baumeister, Philipp, Ulrich Harréus, Schwenk-Zieger, Sabina, Maximilian Reiter, Philipp Baumeister, Reiter, Maximilian, Sabina Schwenk-Zieger, Harreus, Ulrich   +7 more
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The role of recombinant epidermal growth factor and serotonin in the stimulation of tumor growth in a SCCHN xenograft model

, 2012
One challenge of squamous cell carcinoma of the head and neck (SCCHN) chemotherapy is a small percentage of tumor cells that arrest in the G0 phase of the cell cycle and are thus not affected by chemotherapy. This could be one reason for tumor recurrence
Arnoldner, Christoph, Geißler, Christin, Eckardt, Anne Gisela, Hambek, Markus, Wagenblast, Jens, Diensthuber, Marc, Stöver, Timo   +6 more
core   +1 more source

The complete family of epidermal growth factor receptors and their ligands are co-ordinately expressed in breast cancer [PDF]

, 2009
The levels of expression of the four receptors and eleven ligands composing the Epidermal Growth Factor family were measured using immunohistochemical staining in one hundred cases of breast cancer. All of the family were expressed to some degree in some
McIntyre, Emmet, Johnson, Colin G., Gullick, William J., Blackburn, Edith, Brown, Philip J.   +4 more
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THE PROGNOSTIC ROLE OF EPIDERMAL GROWTH FACTOR RECEPTOR MUTATION IN COMPLETELY RESECTED AMPULLARY ADENOCARCINOMA

, 2023
The aim of this study is to make a differential diagnosis and prognosis of the amp-ullary adenocarcinoma subtypes. We also investigated the role of prognostic mark-ers PD-1 and PD-L1, and epidermal growth factor receptor (EGFR). Local or locally advanced
Safiye Aktas, Somall, Isil, Salman, Tarik, Tarık Salman, Fatma Husniye Dilek, Cakir, Ebru, Aiacaciogiu, Ahmet, Varol, Umut, Ahmet Alacacioglu, Unlu, Ause Gulden Diniz, ALTUN, ZEKİYE SULTAN, Butun, Osman, Osman Butun, Ebru Cakır, Zekiye Sultan Altun, AKTAŞ, SAFİYE, Dilek, Fatma Husniye, Umut Varol, Ayse Gulden Diniz Unlu, Isil Somali   +19 more
core   +1 more source

Potency and stability of C terminal truncated human epidermal growth factor

, 2000
INTRODUCTION: Epidermal growth factor (EGF) is normally present as EGF(1-53). A variety of C terminal truncated forms have been used in preliminary trials for treating gastrointestinal injury but their relative potency and stability when used in a ...
Lakhoo, K, Berlanga-Acosta, J, Edwards, A. D.; id_orcid, Marchbank, T, Edwards, AD, Fagbemi, A., Calnan, D. P., Sizer, T., Berlanga-Acosta, J., Fagbemi, A, Marchbank, T., Sizer, T, Playford, RJ, Playford, R. J., Lakhoo, K., Calnan, DP   +15 more
core   +1 more source