Results 131 to 140 of about 648,509 (314)

Cluster analysis of deterioration sites after first-line epidermal growth factor receptor-tyrosine kinase inhibitor in epidermal growth factor receptor mutated non-small cell lung cancer [PDF]

, 2022
Shinichiro Okauchi, Kunihiko Miyazaki, Hiroaki Satoh   +2 more
openalex   +1 more source

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

Purified plasma membranes inhibit polypeptide growth factor-induced DNA synthesis in subconfluent 3T3 cells. [PDF]

, 1984
Plasma membranes derived from NR-6 cells, a variant line of Swiss mouse 3T3 cells that does not have cell surface receptors for epidermal growth factor (EGF), inhibited EGF-induced stimulation of DNA synthesis by 50% in serum-starved, subconfluent 3T3 ...
Fox, CF, Matiuck, NV, Peterson, SW, Vale, RD   +3 more
core  

Printing Nacre‐Mimetic MXene‐Based E‐Textile Devices for Sensing and Breathing‐Pattern Recognition Using Machine Learning

Advanced Functional Materials, EarlyView.
This study presents a Ti3C2Tx MXene/WPU nacre‐mimetic nanomaterial as a printable ink for direct‐write printing onto textiles‐based sensors. The resulting wearable device demonstrates high sensitivity, biocompatibility, and mechanical strength. Furthermore, NFC‐enabled humidity sensor produces time‐series data, which informs a machine learning ...
Lulu Xu, Wenqing Chen, Qian Li, Rohit Gupta, Biswajoy Bagchi, Laurence B. Lovat, Manish K. Tiwari   +6 more
wiley   +1 more source

An epidermal growth factor receptor compound mutation of L858R with S768I in advanced non-small-cell lung cancer: a case report

Journal of Medical Case Reports
Background In the current treatment landscape for non-small cell lung cancers, epidermal growth factor receptor-tyrosine kinase inhibitors have emerged as a well-established treatment option for patients with advanced or metastatic disease.
Sara Boukansa, Ismail Mouhrach, Fatima El Agy, Laila Bouguenouch, Mounia Serraj, Bouchra Amara, Yassine Ouadnouni, Mohamed Smahi, Badreeddine Alami, Nawfel Mellas, Zineb Benbrahim, Hinde El Fatemi   +11 more
doaj   +1 more source

Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes

Advanced Functional Materials, EarlyView.
Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth, Neal I. Callaghan, Locke Davenport Huyer   +2 more
wiley   +1 more source

Pertuzumab in human epidermal growth-factor receptor 2-positive breast cancer: clinical and economic considerations

International Journal of Women's Health, 2014
Nathan WD Lamond, Tallal YounisDepartment of Medicine, Dalhousie University at the Queen Elizabeth II Health Sciences Centre, Halifax, NS, CanadaAbstract: In the absence of specific therapy, the 15%–20% of breast cancers demonstrating human ...
Lamond NW, Younis T
doaj  

Transmembrane signalling at epidermal growth factor receptors overexpressed in NIH 3T3 cells. Phosphoinositide hydrolysis, cytosolic Ca2+ increase and alkalinization correlate with epidermal-growth-factor-induced cell proliferation [PDF]

, 1988
Atanasio Pandiella, Laura Beguinot, Thierry Velu, Jacopo Meldolesi   +3 more
openalex   +1 more source

Supplementary Figure 2 from Loss of PTEN Expression by Blocking Nuclear Translocation of EGR1 in Gefitinib-Resistant Lung Cancer Cells Harboring Epidermal Growth Factor Receptor–Activating Mutations

, 2023
Chizuko Yamamoto, Yuji Basaki, Akihiko Kawahara, Kazutaka Nakashima, Masayoshi Kage, Hiroto Izumi, Kimitoshi Kohno, Hidetaka Uramoto, Kosei Yasumoto, Michihiko Kuwano, Mayumi Ono   +10 more
openalex   +1 more source

Additively Manufactured Diamond for Energy Scavenging and Wireless Power Transfer in Implantable Devices

Advanced Functional Materials, EarlyView.
Additive manufacturing is expanding beyond mechanical prosthetics into microelectronic implants. This work presents a diamond‐titanium hybrid that enables wireless power transfer, localized heating, and flow sensing. The use of additive manufacturing combined with the biocompatibility of the diamond‐titanium hybrid material paves the way toward new ...
Joshua Zarins, Daniel De Maria, Alan Jones, Deepak Sharma, Amir Ebrahimi, Zhangyu Xu, Omid Kavehei, Peter C. Sherrell, Kate Fox, Arman Ahnood   +9 more
wiley   +1 more source