Results 151 to 160 of about 1,962,623 (304)
From Payload‐First Toward Dual‐Mechanism Antibody–Drug Conjugates
Conjugation converts potent antibodies into underexposed carriers. This perspective defines the antibody exposure deficit and maps a mechanism‐first design space from payload‐first to antibody‐first ADC architectures, integrating DAR, linker chemistry, and Fc engineering to guide rational design of constructs that balance targeted cytotoxicity with ...
Xavier Pivot +3 more
wiley +1 more source
Epidermal growth factor receptor-targeted near-infrared photoimmunotherapy for malignant pleural mesothelioma. [PDF]
Kano M +7 more
europepmc +1 more source
By growing a conformal ZIF‐8 protective layer directly on antibody‐functionalized microneedles, this work converts a fragile biosensing interface into a thermostable diagnostic platform. The MOF@MN patch enables minimally invasive NGAL detection from dermal ISF while supporting cold‐chain‐independent storage and transport for decentralized kidney ...
Yixuan Wang +10 more
wiley +1 more source
Tubulogenesis of bovine uterine glands by epidermal growth factor and collagen I in 3D culture systems. [PDF]
Sugino Y +5 more
europepmc +1 more source
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma +15 more
wiley +1 more source
Correction: Q-CaDD: accelerating in silico methodologies with quantum computation and machine learning for Epidermal growth factor receptor. [PDF]
Badarala L.
europepmc +1 more source
Epidermal growth factor receptor targeting and challenges in glioblastoma.
A. H. Thorne, C. Zanca, F. Furnari
semanticscholar +1 more source

