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Epidermal growth factor and transforming growth factor α
Baillière's Clinical Endocrinology and Metabolism, 1991I have attempted here to outline the basic biochemical knowledge that we have now secured on the EGF family of proteins. In the future we will learn much more about the differential role of EGF versus TGF-alpha, about the physiological significance of amphiregulin, the newest member of this family, and about the roles of TGF-alpha and amphiregulin in ...
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Epidermal growth factor and transforming growth factor α
British Medical Bulletin, 1989This review describes the discovery and initial characterization of the epidermal growth factors (EGFs) and transforming growth factors alpha (TGF alpha), the biosynthesis and tissue distribution of these molecules and a brief description of the effects of these molecules in culture and animals.
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Cell Biology International, 1995
ABSTRACTEpidermal growth factor (EGF) is a single polypeptide of 53 amino acid residues which is involved in the regulation of cell proliferation. Egf exerts its effects in the target cells by binding to the plasma membrane located EGF receptor. The EGF receptor is a transmembrane protein tyrosine kinase.
J, Boonstra +5 more
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ABSTRACTEpidermal growth factor (EGF) is a single polypeptide of 53 amino acid residues which is involved in the regulation of cell proliferation. Egf exerts its effects in the target cells by binding to the plasma membrane located EGF receptor. The EGF receptor is a transmembrane protein tyrosine kinase.
J, Boonstra +5 more
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Epidermal growth factor receptor mutations in lung cancer
Nature Reviews. Cancer, 2007Sreenath V. Sharma +3 more
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Epidermal Growth Factor and Related Growth Factors
International Journal of Dermatology, 1991R A, Yates +3 more
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Journal of the American Medical Association (JAMA), 2003
M. Kris +15 more
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M. Kris +15 more
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2013
The epidermal growth factor family includes a number of cytokines inducing the proliferation of epithelial cells. The founding member (EGF) is a small protein containing 53 aminoacids and 3 disulfide bonds inducing the proliferation of cells sharing its receptor (EGFR), a member of the Erb family widely used as target of anti-tumoral biomedicines ...
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The epidermal growth factor family includes a number of cytokines inducing the proliferation of epithelial cells. The founding member (EGF) is a small protein containing 53 aminoacids and 3 disulfide bonds inducing the proliferation of cells sharing its receptor (EGFR), a member of the Erb family widely used as target of anti-tumoral biomedicines ...
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Epidermal growth factor-related peptides and their receptors in human malignancies.
Critical reviews in oncology/hematology, 1995D. Salomon +3 more
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Epidermal growth factor receptor (EGFR) signaling in cancer.
Gene, 2006N. Normanno +9 more
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