Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi +7 more
wiley +1 more source
Radiation therapy plus osimertinib <i>vs</i> osimertinib alone in epidermal growth factor receptor mutated non-small cell lung cancer: A systematic review. [PDF]
Javed M +14 more
europepmc +1 more source
This study developed a double‐network hydrogel with piezoelectric properties, exhibiting excellent antibacterial activity and promoting fibroblast migration, angiogenesis, and lymphangiogenesis through piezoelectric stimulation, thereby accelerating the healing of infected chronic wounds.
Xiang Li +7 more
wiley +1 more source
Multi-omics profiling reveals epidermal growth factor as a potential biomarker and therapeutic target in lupus nephritis and ANCA-associated vasculitis with rapidly progressive glomerulonephritis. [PDF]
Xu M +8 more
europepmc +1 more source
Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas +10 more
wiley +1 more source
Folliculitis Decalvans Due to Epidermal Growth Factor Inhibitor
Aurora Maria Alessandrini +2 more
doaj +1 more source
Comparison of CT-based radiomics models for the prediction of human epidermal growth factor receptor 2 status in gastric cancer. [PDF]
Wang X +7 more
europepmc +1 more source
Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen +13 more
wiley +1 more source
Evaluating Tumor Burden as a Predictive Biomarker for Epidermal Growth Factor Receptor Targeted Kinase Inhibitor Therapy in Advanced Non-Small Cell Lung Cancer. [PDF]
Terashima R +23 more
europepmc +1 more source

