Results 261 to 270 of about 410,903 (309)
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Radioimmunoassay of Epidermal Growth Factor
Endocrinology, 1972Epidermal growth factor (EGF) is a biologically active polypeptide extracted from male mouse submaxillary glands. It exists either alone or complexed with an arginine esterase. It causes generalized epidermal growth and keratinization in the immature mouse and results in precocious tooth eruption and eye-opening that are the basis for an EGF bioassay ...
R L, Byyny, D N, Orth, S, Cohen
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Baillière's Clinical Gastroenterology, 1996
Despite the wealth of information concerning EGF and its related peptides, its precise role in the control of gastrointestinal functions is still not fully resolved. However, there is no doubt that it can have some very potent effects on the gastrointestinal tract. These may be related to the control of growth and development and to the regular control
R A, Goodlad, N A, Wright
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Despite the wealth of information concerning EGF and its related peptides, its precise role in the control of gastrointestinal functions is still not fully resolved. However, there is no doubt that it can have some very potent effects on the gastrointestinal tract. These may be related to the control of growth and development and to the regular control
R A, Goodlad, N A, Wright
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Epidermal growth factor receptors
Molecular and Cellular Biochemistry, 1981EGF-Rs are cell membrane glycoproteins of wide distribution. They have not yet been fully characterized or purified but are probably molecules of 170-190,000 mol. wt. in most cells. The growth factor EGF binds and will saturate cell surface receptors with a KA of about 5 X 10(9) M-1 although a receptor class with an affinity in excess of 10(10) M-1 has
E D, Adamson, A R, Rees
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Epidermal growth factor in blood
Regulatory Peptides, 1986The presence of receptors for epidermal growth factor (EGF) in a wide variety of human tissues and also some tumours indicates an as yet undefined role for EGF and it is therefore necessary to know precise concentrations in blood and other fluids. We have investigated the occurrence of EGF in the circulation and found that in platelet rich plasma, EGF ...
A P, Savage +3 more
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Biochemistry, 1989
Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) compete with each other for binding to the EGF receptor. These two growth factors have similar actions, but there are distinguishable differences in their biological activities. It has never been clear how this one receptor can mediate different responses.
M E, Winkler +3 more
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Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) compete with each other for binding to the EGF receptor. These two growth factors have similar actions, but there are distinguishable differences in their biological activities. It has never been clear how this one receptor can mediate different responses.
M E, Winkler +3 more
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Epidermal growth factor and transforming growth factor α
Baillière's Clinical Endocrinology and Metabolism, 1991I have attempted here to outline the basic biochemical knowledge that we have now secured on the EGF family of proteins. In the future we will learn much more about the differential role of EGF versus TGF-alpha, about the physiological significance of amphiregulin, the newest member of this family, and about the roles of TGF-alpha and amphiregulin in ...
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Epidermal growth factor and transforming growth factor α
British Medical Bulletin, 1989This review describes the discovery and initial characterization of the epidermal growth factors (EGFs) and transforming growth factors alpha (TGF alpha), the biosynthesis and tissue distribution of these molecules and a brief description of the effects of these molecules in culture and animals.
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Cell Biology International, 1995
ABSTRACTEpidermal growth factor (EGF) is a single polypeptide of 53 amino acid residues which is involved in the regulation of cell proliferation. Egf exerts its effects in the target cells by binding to the plasma membrane located EGF receptor. The EGF receptor is a transmembrane protein tyrosine kinase.
J, Boonstra +5 more
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ABSTRACTEpidermal growth factor (EGF) is a single polypeptide of 53 amino acid residues which is involved in the regulation of cell proliferation. Egf exerts its effects in the target cells by binding to the plasma membrane located EGF receptor. The EGF receptor is a transmembrane protein tyrosine kinase.
J, Boonstra +5 more
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Epidermal Growth Factor and Related Growth Factors
International Journal of Dermatology, 1991R A, Yates +3 more
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1991
Polypeptide growth factors have attracted considerable interest since the initial description of nerve growth factor (NGF) in 1951 (Levi-Montalcini and Hamburger 1951) and, subsequently, the identification of epidermal growth factor (EGF) in 1962 (Cohen 1962).
R. V. Nardi, A. Guglietta, I. Parikh
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Polypeptide growth factors have attracted considerable interest since the initial description of nerve growth factor (NGF) in 1951 (Levi-Montalcini and Hamburger 1951) and, subsequently, the identification of epidermal growth factor (EGF) in 1962 (Cohen 1962).
R. V. Nardi, A. Guglietta, I. Parikh
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