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Epidermal growth factor and transforming growth factor α
Baillière's Clinical Endocrinology and Metabolism, 1991I have attempted here to outline the basic biochemical knowledge that we have now secured on the EGF family of proteins. In the future we will learn much more about the differential role of EGF versus TGF-alpha, about the physiological significance of amphiregulin, the newest member of this family, and about the roles of TGF-alpha and amphiregulin in ...
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Epidermal growth factor and transforming growth factor α
British Medical Bulletin, 1989This review describes the discovery and initial characterization of the epidermal growth factors (EGFs) and transforming growth factors alpha (TGF alpha), the biosynthesis and tissue distribution of these molecules and a brief description of the effects of these molecules in culture and animals.
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Archives of Pathology & Laboratory Medicine, 2006
Antonio C. Wolff+22 more
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Antonio C. Wolff+22 more
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Epidermal growth factor receptor mutations in lung cancer
Nature Reviews. Cancer, 2007Sreenath V. Sharma+3 more
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Biochemical and Biophysical Research Communications, 1990
The capacity of epidermal growth factor (EGF) or transforming growth factor-alpha (TGF-alpha) to induce internalization and degradation of the EGF receptor was compared in NIH-3T3 cells expressing the human EGF receptor. This study was initiated following the observation that TGF-alpha was much less efficient relative to EGF in generating a Mr = 125 ...
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The capacity of epidermal growth factor (EGF) or transforming growth factor-alpha (TGF-alpha) to induce internalization and degradation of the EGF receptor was compared in NIH-3T3 cells expressing the human EGF receptor. This study was initiated following the observation that TGF-alpha was much less efficient relative to EGF in generating a Mr = 125 ...
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Epidermal Growth Factor and Related Growth Factors
International Journal of Dermatology, 1991Ronald E. Gates+3 more
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Epidermal growth factor-related peptides and their receptors in human malignancies.
Critical reviews in oncology/hematology, 1995D. Salomon+3 more
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