Results 61 to 70 of about 2,008,123 (283)

Serum Epidermal Growth Factor in Cancer Breast

Journal of High Institute of Public Health, 2007
Several prognostic factors are evaluated in the breast carcinoma and there is a need for new markers for better discrimination of the biologic differences in the primary tumor.
El-Attar HA, Moghazy TF, Fadaly GA, Abou Diba MI   +3 more
doaj   +1 more source

Impact of epidermal growth factor receptor gene expression level on clinical outcomes in epidermal growth factor receptor mutant lung adenocarcinoma patients taking first-line epidermal growth factor receptor–tyrosine kinase inhibitors

Tumor Biology, 2017
Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are first-choice treatments for advanced non-small-cell lung cancer patients harboring EGFR mutations.
Huang-Chih Chang, Yu-Mu Chen, Chia-Cheng Tseng, Kuo-Tung Huang, Chin-Chou Wang, Yung-Che Chen, Chien-Hao Lai, Wen-Feng Fang, Hsu-Ching Kao, Meng-Chih Lin   +9 more
doaj   +1 more source

Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium [PDF]

, 2014
Breast cancer risk factors and clinical outcomes vary by tumour marker expression. However, individual studies often lack the power required to assess these relationships, and large-scale analyses are limited by the need for high throughput, standardized
Ali, H Raza, Benitez, Javier, Blomqvist, Carl, Blows, Fiona M, Bolla, Manjeet K, Brinton, Louise, Brock, Ian W, Broeks, Annegien, Brook, Mark N, Caldas, Carlos, Couch, Fergus J, Coulson, Penny, Cox, Angela, Cross, Simon S, Daley, Frances, Dawson, Sarah-Jane, Devillee, Peter, Easton, Douglas F, Fagerholm, Rainer, Figueroa, Jonine, García-Closas, Montserrat, Gazinska, Patrycja, Heikkilä, Päivi, Hollestelle, Antoinette, Howat, William J, Johnson, Nicola, Jones, Louise, Kataja, Vesa, Kosma, Veli-Matti, Lissowska, Jolanta, Mannermaa, Arto, McDuffus, Leigh-Anne, Menéndez, Primitiva, Mesker, Wilma E, Miller, Jodi, Morris, Lorna, Nevanlinna, Heli, Olson, Janet E, Perez, Jose Ignacio Arias, Pharoah, Paul D, Pinder, Sarah, Provenzano, Elena, Reed, Malcolm W, Sanders, Joyce, Sawyer, Elinor J, Schmidt, Marjanka K, Seyaneve, Caroline M, Sherman, Mark E, Sironen, Reijo, van Deurzen, Carolien H M, Visscher, Daniel, Wesseling, Jelle   +51 more
core   +5 more sources

Pharmacology of Epidermal Growth Factor Inhibitors

The International Journal of Biological Markers, 2007
Research into the molecular bases of malignant diseases has yielded the development of many novel agents with potential antitumor activity. Evidence for a causative role for the epidermal growth factor receptor (EGFR), which is now regarded as an excellent target for cancer chemotherapy in human cancer, leads to the development of EGFR inhibitors. Two
Erika Cecchin, Sara Masier, Giuseppe Corona, E. De Mattia, Paola Biason, Giuseppe Toffoli   +5 more
openaire   +4 more sources

Wound-Healing Effect of Antheraea pernyi Epidermal Growth Factor

Insects, 2022
To evaluate the wound-healing effect of Antheraea pernyi epidermal growth factor (ApEGF), we performed the sequence analysis, cloning, and prokaryotic expression of cDNA from the ApEGF gene, examined the transcriptional changes, and investigated the ...
Yu-Lan Piao, Chun-Yang Zhang, Yue Zhang, Kun Qian, Ying Zhou, Jun-Yan Liu, Young-Cheol Chang, Hoon Cho, Dubok Choi   +8 more
doaj   +1 more source

Transcytosis of epidermal growth factor. The epidermal growth factor receptor mediates uptake but not transcytosis

Journal of Biological Chemistry, 1991
Madin-Darby canine kidney (MDCK) cells polarize and generate distinct apical and basolateral membrane domains when grown on permeable filter supports. Under these conditions, they transcytose fluid-phase markers. Recently, receptor-mediated transcytosis of epidermal growth factor (EGF) across MDCK cells has been reported (Maratos-Flier, E., Kao, C.-Y ...
Kai Simons, E D Adamson, A W Brändli
openaire   +3 more sources

Role of Epidermal Growth Factor Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage [PDF]

, 2018
Chronickidneydisease (CKD)ischaracterized bypersistent inflammationandprogressive fibrosis,ultimatelyleadingto end-stage renal disease. Although many studies have investigated the factors involved in the progressive deterioration of renal function, current
Goldschmeding, Roel, Morgado-Pascual, José L., Rayego Mateos, Sandra, Rodrigues-Diez, Raul, Ruiz-Ortega, Marta, Valdivielso Revilla, José Manuel, Valentijn, Floris   +6 more
core   +2 more sources

Skin Toxicities Induced by Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors and their Influence on Treatment Adjustments in Lung Cancer Patients

Acta Dermato-Venereologica
Skin toxicities caused by epidermal growth factor receptor tyrosine kinase inhibitors can affect patient quality of life and lead to treatment adjustments, including dose reduction or discontinuation.
Ji Su Lee, Jimin Woo, Tae Min Kim, Namkyu Kim, Bhumsuk Keam, Seong Jin Jo   +5 more
doaj   +1 more source

Molecular Docking Optimization in the Context of Multi-Drug Resistant and Sensitive EGFR Mutants

Molecules, 2016
The human Epidermal Growth Factor (EGFR) plays an important role in signaling pathways, such as cell proliferation and migration. Mutations like G719S, L858R, T790M, G719S/T790M or T790M/L858R can alter its conformation, and, therefore, drug responses ...
María Jesús García-Godoy, Esteban López-Camacho, José García-Nieto, Antonio J. Nebro, José F. Aldana-Montes   +4 more
doaj   +1 more source

Epidermal growth factor and keratinocyte growth factor differentially regulate epidermal migration, growth, and differentiation

Wound Repair and Regeneration, 2000
Various growth factors such as epidermal growth factor and keratinocyte growth factor have been reported to promote wound closure and epidermal regeneration. In the present study epidermis reconstructed on de‐epidermized dermis was used to investigate the effects of epidermal growth factor and keratinocyte growth factor on keratinocyte proliferation ...
Gibbs, S., Silva Pinto, A.N., Murli, S., Huber, M., Hohl, D., Ponec, M.   +5 more
openaire   +4 more sources