Results 81 to 90 of about 2,008,123 (283)

Epidermal Growth Factor–PEG Functionalized PAMAM-Pentaethylenehexamine Dendron for Targeted Gene Delivery Produced by Click Chemistry [PDF]

, 2011
Aim of this study was the site-specific conjugation of an epidermal growth factor (EGF)-polyethylene glycol (PEG) chain by click chemistry onto a poly(amido amine) (PAMAM) dendron, as a key step toward defined multifunctional carriers for targeted gene ...
Balogh L., Bartlett D. W., Blessing T., Boeckle S., Boussif O., Carboni B., Carlin C. R., Choi J. S., Christian Dohmen, Davis M. E., Davis M. E., de Bruin K., Ernst Wagner, Esfand R., Haijun Yu, Hua C., Iyer J., Kannan R. M., Kataoka K., Kircheis R., Kircheis R., Kloeckner J., Kloeckner J., Kursa M., Lee J. W., Li S. D., Luo D., Lutz J. F., Maeda H., Maiti P. K., Meyer M., Navarro G., Nie Y., Ogris M., Plank C., Plank C., Russ V., Russ V., Russ V., Schaffert D., Shir A., Simoes S., Svenson S., Tomalia D. A., Tomalia D. A., von Gersdorff K., Wagner E., Wagner E., Walker G. F., Wolschek M. F., Wood K. C., Yellepeddi V. K., Yu H., Yu H., Yu Nie, Yunqiu Li, Zhang X. Q., Zhao X., Zou S. M., Zugates G. T.   +59 more
core   +1 more source

Epidermal Growth Factor and Fibroblast Growth Factor-2 Have Different Effects on Neural Progenitors in the Adult Rat Brain

Journal of Neuroscience, 1997
Neurons and glia are generated throughout adulthood from proliferating cells in two regions of the rat brain, the subventricular zone (SVZ) and the hippocampus.
H. Kuhn, Jü Rgen Winkler, G. Kempermann, L. Thal, F. Gage, T. Palmer, L. J. Fisher, Mireya Nadal-Vicens, Mary Lynn   +8 more
semanticscholar   +1 more source

Epidermal Growth Factor Receptor Pathway [PDF]

Journal of Thoracic Oncology, 2010
The epidermal growth factor receptor (EGFR) pathway has provided a new therapeutic target in non-small cell lung cancer (NSCLC). Two EGFR tyrosine kinase inhibitors (TKIs) are being used globally as systemic treatment in advanced NSCLC. In addition, clinical observations with EGFR TKIS led to the discovery of EGFR activating mutations, which has ...
openaire   +3 more sources

The clinical effectiveness and cost-effectiveness of cetuximab (mono- or combination chemotherapy), bevacizumab (combination with non-oxaliplatin chemotherapy) and panitumumab (monotherapy) for the treatment of metastatic colorectal cancer after first-line chemotherapy (review of technology appraisal No.150 and part review of technology appraisal No. 118): a systematic review and economic model [PDF]

, 2013
Colorectal cancer is the third most commonly diagnosed cancer in the UK after breast and lung cancer. People with metastatic disease who are sufficiently fit are usually treated with active chemotherapy as first- or second-line therapy.
Cooper, Chris, Crathorne, Louise, Hoyle, M, Hyde, C, Jones-Hughes, T, Napier, Mark, Peters, J, Tappenden, P   +7 more
core   +2 more sources

EGFL7 participates in regulating biological behavior of growth hormone–secreting pituitary adenomas via Notch2/DLL3 signaling pathway

Tumor Biology, 2017
Growth hormone–secreting pituitary adenoma accounts for about 20% of the third most common intracranial neoplasm—pituitary adenomas—which makes up 15% of all intracranial tumors.
Jianpeng Wang, Qian Liu, Hua Gao, Dehong Wan, Chuzhong Li, Zhaojian Li, Yazhuo Zhang   +6 more
doaj   +1 more source

A comprehensive pathway map of epidermal growth factor receptor signaling

Molecular Systems Biology, 2005
The epidermal growth factor receptor (EGFR) signaling pathway is one of the most important pathways that regulate growth, survival, proliferation, and differentiation in mammalian cells.
Kanae Oda, Yukiko Matsuoka, Akira Funahashi, Hiroaki Kitano   +3 more
semanticscholar   +1 more source

The Molecular Perspective: Epidermal Growth Factor [PDF]

The Oncologist, 2003
Abstract Learning Objectives After completing this course, the reader will be able to: Describe the structure and function of epidermal growth factor and its role in cancer development and treatment.
openaire   +4 more sources

HER2 Overexpression in Borderline and Malignant Ovarian Tumors: A Cross-sectional Study in an Iranian Population and Literature Review

Middle East Journal of Cancer, 2018
Background: Different studies have investigated the overexpression of human epidermal growth factor receptor 2 in ovarian cancers, in addition to the association between the level of its overexpression and tumor characteristics (tumor grade, subtype ...
Elham Asadinejad, Afshin Abdirad, Fatemeh Nili, Vahid Soleimani   +3 more
doaj  

The effect of distant metastases sites on survival in de novo stage-IV breast cancer: A SEER database analysis

Tumor Biology, 2017
To investigate the effect of distant metastases sites on survival in patients with de novo stage-IV breast cancer. From 2010 to 2013, patients with a diagnosis of de novo stage-IV breast cancer were identified using the Surveillance, Epidemiology, and ...
San-Gang Wu, Hui Li, Li-Ying Tang, Jia-Yuan Sun, Wen-Wen Zhang, Feng-Yan Li, Yong-Xiong Chen, Zhen-Yu He   +7 more
doaj   +1 more source

Serum epidermal growth factor concentrations in healthy men

Revista Cubana de Medicina Militar
Introduction: Despite the documented importance of epidermal growth factor in health, tiny information is available on its serum concentrations. Objective: To describe the behaviour of serum epidermal growth factor.
Héctor José Pérez Hernández, Danay Saavedra Hernández, Tania Crombet Ramos   +2 more
doaj