Lipocalin-2 Regulates Epidermal Growth Factor Receptor Intracellular Trafficking
Cell Reports, 2019 Summary: Epidermal growth factor receptor (EGFR) activation and lipocalin-2 (Lcn2) expression are frequently observed in the same pathological contexts, such as cancers or chronic kidney disease (CKD).
Lucie Yammine +4 more
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Cytoplasmic domains determine signal specificity, cellular routing characteristics and influence ligand binding of epidermal growth factor and insulin receptors. [PDF]
, 1989 Heimo Riedel +4 more
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Pushing Radiative Cooling Technology to Real Applications
Advanced Materials, EarlyView.Radiative cooling controls surface optical properties for solar and thermal radiation, offering solutions for global warming and energy savings. Despite significant advances, key challenges remain: optimizing optical efficiency, maintaining aesthetics, preventing overcooling, enhancing durability, and enabling scalable production.
Chongjia Lin +8 more
wiley +1 more source
Ligand-mediated internalization, recycling, and downregulation of the epidermal growth factor receptor in vivo. [PDF]
, 1989 W H Lai +6 more
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A Bio‐Inspired Perspective on Materials Sustainability
Advanced Materials, EarlyView.This perspective discusses natural materials as inspiration for sustainable engineering designs and the processing of materials. First, circularity, longevity, parsimony, and activity are presented as essential material paradigms. The perspective then uses many examples of natural and technical materials to introduce principles such as oligo ...
Wolfgang Wagermaier +2 more
wiley +1 more source
Effects of tumor necrosis factor and epidermal growth factor on cell morphology, cell surface receptors, and the production of tissue inhibitor of metalloproteinases and IL-6 in human microvascular endothelial cells. [PDF]
, 1989 Masasumi Mawatari +7 more
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Advanced Materials, EarlyView.Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li +3 more
wiley +1 more source
Clinical Interventions in Aging, 2016 Yohei Tanaka,1,2 Jun Nakayama2 1Department of Plastic Surgery, Clinica Tanaka Plastic, Reconstructive Surgery and Anti-aging Center, 2Department of Molecular Pathology, Shinshu University Graduate School of Medicine, Matsumoto, Nagano, Japan Background
Tanaka Y, Nakayama J
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Engineering CAR‐T Therapeutics for Enhanced Solid Tumor Targeting
Advanced Materials, EarlyView.CART cell therapy has proven effective for blood cancers but struggles with solid tumors due to diverse antigens and complex environments. Recent efforts focus on improving CAR design and validation platforms. Advances in protein engineering, machine learning, and organoid systems aim to enhance CAR‐T therapy against solid tumors.
Danqing Zhu +4 more
wiley +1 more source