Results 151 to 160 of about 5,980,424 (294)

Evolution of the clonogenic potential of human epidermal stem/progenitor cells with age

Stem Cells and Cloning: Advances and Applications, 2012
Olivia Zobiri, Nathalie Deshayes, Michelle Rathman-JosserandDepartment of Biological Research, L'Oréal Advanced Research, Clichy Cedex, FranceAbstract: A number of clinical observations have indicated that the regenerative potential ...
Zobiri O, Deshayes N, Rathman-Josser, M
doaj  

The Rho guanosine nucleotide exchange factors Vav2 and Vav3 modulate epidermal stem cell function. [PDF]

Oncogene, 2022
Lorenzo-Martín LF, Menacho-Márquez M, Fernández-Parejo N, Rodríguez-Fdez S, Pascual G, Abad A, Crespo P, Dosil M, Benitah SA, Bustelo XR.   +9 more
europepmc   +1 more source

TED1 Promotes the Assembly of SCFD3‐D14‐D53 to Reinforce Strigolactone Signaling in Rice

Advanced Science, EarlyView.
This study identifies TED1 as a positive regulator of strigolactones (SL) signaling in rice. The ted1 mutants display dwarfism and increased tillering with significantly reduced SLs sensitivity. Through its longer C‐terminal region, TED1 interacts with D53 and D14 to promote the assembly of SCFD3‐D14‐D53, thereby facilitating the efficient ...
Sheng Luo, Chuanyin Wu, Miao Feng, Wenfan Luo, Rong Miao, Jinsheng Qian, Fan Wang, Chunlei Zhou, Bojuan Liu, Jiale Shao, Ziqi Xun, Yehui Xiong, Zhichao Zhao, Cailin Lei, Shanshan Zhu, Yulong Ren, Xin Wang, Xiuping Guo, Haiyang Wang, Zichao Li, Zhijun Cheng, Qibing Lin, Jianmin Wan   +22 more
wiley   +1 more source

Gradual differentiation uncoupled from cell cycle exit generates heterogeneity in the epidermal stem cell layer. [PDF]

Nat Cell Biol, 2022
Cockburn K, Annusver K, Gonzalez DG, Ganesan S, May DP, Mesa KR, Kawaguchi K, Kasper M, Greco V.   +8 more
europepmc   +1 more source

Hematopoietic stem cell responsiveness to exogenous signals is limited by Caspase-3

, 2008
SummaryLimited responsiveness to inflammatory cytokines is a feature of adult hematopoietic stem cells and contributes to the relative quiescence and durability of the stem cell population in vivo.
Riese, Matthew J, Woo, Minna, Karlsson, Göran, Milne, Craig D, Lo Celso, Cristina, Karlsson, Göran,, Scadden, David T, Fleming, Heather E, Paige, Christopher J, Karlsson, Stefan, Janzen, Viktor, Reynolds, Griffin, Karlsson, Stefan,, Riedt, Tamara, Lund University.   +14 more
core   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

A reductionist approach to determine the effect of cell-cell contact on human epidermal stem cell differentiation. [PDF]

Acta Biomater, 2022
Louis B, Tewary M, Bremer AW, Philippeos C, Negri VA, Zijl S, Gartner ZJ, Schaffer DV, Watt FM.   +8 more
europepmc   +1 more source

Machine Learning‐Driven Design of Multicomponent Bone Inorganic Matrix Mimicking Scaffolds for Osteogenesis Enhanced by Neurogenesis

Advanced Science, EarlyView.
Schematic illustration of development of experimental datasets and algorithm models, screening and preparation of the scaffolds and their applications in vivo. ABSTRACT Bone defects require materials with osteogenic, neurogenic, and angiogenic activity, yet designing such materials within high‐dimensional compositional spaces remains challenging. Here,
Kunlu Lin, Ying Yang, Chuyao Zhou, Hanyue Mao, Zhiquan Zhang, Libangxi Liu, Xiaoying Yu, Haoming Liu, Long Liu, Xiaoyan Wang   +9 more
wiley   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Pgc-1α controls epidermal stem cell fate and skin repair by sustaining NAD⁺ homeostasis during aging. [PDF]

Mol Metab, 2022
Wong W, Crane ED, Zhang H, Li J, Day TA, Green AE, Menzies KJ, Crane JD.   +7 more
europepmc   +1 more source