Results 201 to 210 of about 5,980,424 (294)

Human epidermal stem cell differentiation is modulated by specific lipid subspecies. [PDF]

Proc Natl Acad Sci U S A, 2020
Vietri Rudan M, Mishra A, Klose C, Eggert US, Watt FM.   +4 more
europepmc   +1 more source

The GPX3‐VCAM1 Axis Gates Pro‐Fibrotic Tubule Cell Fate in Hyperuricemic Nephropathy

Advanced Science, EarlyView.
Hyperuricemia induces NLRP3 inflammasome signaling activation and downregulation of GPX3 in proximal tubular epithelial cells, leading to oxidative stress–driven VCAM1 upregulation, emergence of pro‐fibrotic proximal tubule cells, macrophage recruitment, and renal fibrosis.
Yunfei Qi, Qiang Zhao, Yue Lve, Yaming Yuan, Tingting Zhou, Yue Yuan, Dexi Wu, Yifan Tang, Yan Liu, Zhigang Li, Chunping Jiang, Qiurong Ding   +11 more
wiley   +1 more source

Inference of a three-gene network underpinning epidermal stem cell development in <i>Caenorhabditis elegans</i>. [PDF]

iScience
Brożek A, Ceccarelli A, Sølvsten Jørgensen AC, Hintze M, Shahrezaei V, Barkoulas M.   +5 more
europepmc   +1 more source

Corrigendum: The Effects of the 3-OH Group of Kaempferol on Interfollicular Epidermal Stem Cell Fate. [PDF]

Ann Dermatol, 2020
Chae JB, Choi HR, Shin JW, Na JI, Huh CH, Park KC.   +5 more
europepmc   +1 more source

Cryptic genetic variation in a heat shock protein modifies the outcome of a mutation affecting epidermal stem cell development in C. elegans. [PDF]

Nat Commun, 2021
Koneru SL, Hintze M, Katsanos D, Barkoulas M.   +3 more
europepmc   +1 more source

A Metabolic‐Epigenetic Axis of AARS1/IGF2BP3‐K280 Lactylation Sustains Endometrial Cancer Stemness and Recurrence

Advanced Science, EarlyView.
Lactate‐driven endometrial cancer relapse is mediated by enzymatic protein modification. Elevated lactate levels activate AARS1, which catalyzes K280 lactylation of IGF2BP3, therefore stabilizing HMGA2 mRNA and promoting tumor stemness and recurrence.
Peng Jiang, Yunfeng Zheng, Chenfan Tian, Yuan Tu, Xiaoxia Chang, Jiaxin Yu, Hangkun Yu, Chunxia Gong, Jie Xiong, Philip N. Baker, Yong Fu, Chao Tong   +11 more
wiley   +1 more source

Epidermal stem cell-derived exosomes improve wound healing by promoting the proliferation and migration of human skin fibroblasts. [PDF]

Burns Trauma
Kang D, Wang X, Chen W, Mao L, Zhang W, Shi Y, Xie J, Yang R.   +7 more
europepmc   +1 more source

Loss of the Epigenetic Mark 5-hmC in Psoriasis: Implications for Epidermal Stem Cell Dysregulation. [PDF]

J Invest Dermatol, 2020
Li F, Yuan CW, Xu S, Zu T, Woappi Y, Lee CAA, Abarzua P, Wells M, Ramsey MR, Frank NY, Wu X, Mandinova A, Frank MH, Lian CG, Murphy GF.   +14 more
europepmc   +1 more source

Phenotypic Robustness of Epidermal Stem Cell Number in C. elegans Is Modulated by the Activity of the Conserved N-acetyltransferase nath-10/NAT10. [PDF]

Front Cell Dev Biol, 2021
Hintze M, Katsanos D, Shahrezaei V, Barkoulas M.   +3 more
europepmc   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

Advanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen, Jiahui Lai, Qiongjiao Zeng, Liangbin Zhou, Boguang Yang, Bin Zhang, Min Wang, Jiajing Zhou, Kieran Lau, Khoon S. Lim, Zhong Alan Li, Rocky S. Tuan   +11 more
wiley   +1 more source