Results 101 to 110 of about 253,312 (306)

Morphological differences in the skin of marble trout <i>Salmo marmoratus</i> and of brown trout <i>Salmo trutta</i>

Folia Histochemica et Cytobiologica, 2012
Despite being genetically very closely related, the marble trout <em>Salmo marmoratus</em> and the brown trout <em>Salmo trutta</em> exhibit marked phenotypic differences, particularly with regard to skin pigmentation ...
Urška Sivka, Karel Halačka, Simona Sušnik Bajec   +2 more
doaj   +1 more source

Chemerin Is an Antimicrobial Agent in Human Epidermis

PLoS ONE, 2013
Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share similar tertiary structure with antibacterial cathelicidins. Recombinant chemerin has antimicrobial activity.
Magdalena Banaś, Katarzyna Zabieglo, G. Kasetty, M. Kapinska-Mrowiecka, J. Borowczyk, J. Drukała, K. Murzyn, Brian A. Zabel, E. Butcher, J. Schroeder, A. Schmidtchen, J. Cichy   +11 more
semanticscholar   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source

Editorial: Novel aspects of the immunological and structural barrier of the epidermis

Frontiers in Molecular Biosciences, 2023
Ryan O’Shaughnessy, John Common, Danuta Gutowska-Owsiak   +2 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Mechanisms of wound repair in crayfish

Invertebrate Survival Journal, 2009
This review describes the complexity of events involved with repair to integumentary wounds and their regulation using the crayfish as a model system. Injuries to integument precipitate a cascade of cellular events that lead to rapid healing of the wound,
X Vafopoulou
doaj  

Single-cell transcriptome sequencing reveals the cell populations and functions associated with stony coral Pocillopora damicornis

Frontiers in Marine Science
IntroductionPocillopora damicornis, a key species of stony corals, has been the subject of considerable scientific study. However, the cellular composition of P.
Wenguang Diao, Shengyao Zhang, Xueying Zhu, Peiqi Wu, Bingyan Du, Zhe Han, Yunqing Liu, Chunpeng He, Zuhong Lu   +8 more
doaj   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

Arthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge, Gabriela Schmajuk, Sristi Sharma, Colleen P. Flanagan, Sara Faghihi‐Kashani, Ning Zhang, Mary A. Whooley   +6 more
wiley   +1 more source