Results 161 to 170 of about 253,312 (306)

Knockdown of filaggrin in a three-dimensional reconstructed human epidermis impairs keratinocyte differentiation.

Journal of Investigative Dermatology, 2014
V. Pendaries, J. Malaisse, Laurence Pellerin, M. Le Lamer, R. Nachat, S. Kežić, A. Schmitt, Carle Paul, Y. Poumay, G. Serre, M. Simon   +10 more
semanticscholar   +1 more source

GPR124 Alleviates Blood–Brain Barrier Disruption by Enhancing Microvascular Endothelial Function after Traumatic Brain Injury

Advanced Science, EarlyView.
Our study reveals the protective role of GPR124 in maintaining BBB integrity and promoting neurological recovery following TBI. It makes a significant contribution by uncovering a novel molecular interaction between GPR124 and FGFBP1 and linking this to activation of the Wnt/β‐catenin signaling pathway in vascular repair mechanisms.
Chen Wang, Lin Cai, Qiuyuan Gong, Yang Yang, Yuqing Liang, Xinyu Niu, Lai Wei, Ze Liu, Shengju Wu, Yinghui Men, Yaohui Tang, Jun Ding, Hengli Tian, Hao Chen   +13 more
wiley   +1 more source

The interplay between epidermal cells and the cutaneous sensory nervous: a systematic review. [PDF]

Front Immunol
Wang F, An X, Fan D, Shang J.
europepmc   +1 more source

PRC2.1 Coordinates Peri‐Nucleolar H3K27me3‐Enriched Heterochromatin Organization and NPM1 Pentamerization to Maintain Nucleolar Integrity

Advanced Science, EarlyView.
PRC2.1(PCL2)‐coordinated H3K27me3‐enriched PNH establishes a spatial scaffold crucial for nucleolar integrity. As a crucial coordinator, PCL2 links PRC2.1 to chromatin organization and NPM1 assembly. This network‐based model reveals how chromatin modifications and nucleolar components cooperatively maintain nucleolar architecture, revealing novel ...
Lina Zhu, Wenqin Wang, Shuyun Chen, Gangyi Zhu, Zhen Wu, Yue Gu, Jingwen Xiong, Xu Zhang, Heng Liu, Kyoichi Isono, Youming Zhang, Jingjing Cao, Xiangzhi Li   +12 more
wiley   +1 more source

Dual-mechanism vitamin C delivery by polyethylene glycol-23 glyceryl distearate-based niosomes via SVCT2 induction and enhanced transdermal penetration. [PDF]

Drug Deliv
Miyoshi T, Keller BC, Nakagawa S, Ashino T, Kaizaki-Mitsumoto A, Numazawa S.   +5 more
europepmc   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

DGAT1 regulates keratinocyte proliferation through the modulation of retinoid homeostasis. [PDF]

J Physiol Biochem
Kwiecień K, Bryniarska-Kubiak N, Morytko A, Uchańska A, Pastuszczak M, Migaczewski M, Cichy J, Kwiecińska P.   +7 more
europepmc   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

Advanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Brassinosteroid controls leaf air space patterning non-cell autonomously by promoting epidermal growth. [PDF]

Development
Fitzsimons JM, Rock AB, De Falbe RL, Fox S, Whitewoods CD.   +4 more
europepmc   +1 more source

Stem cell patterning and fate in human epidermis.

Cell, 1995
P. Jones, S. Harper, Fiona M. Watt
semanticscholar   +1 more source