Results 11 to 20 of about 300,492 (331)
Glucosylceramide synthase activity in murine epidermis: quantitation, localization, regulation, and requirement for barrier homeostasis [PDF]
Journal of Lipid Research, 1998 Ceramides, which derive from the hydrolysis of glucosylceramide (GlcCer), are the predominant lipid species in the stratum corneum and are critical for epidermal permeability barrier homeostasis. UDP-glucose:ceramide glucosyltransferase (GlcCer synthase)
Chujor S.N. Chujor +3 more
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European Medical Journal Dermatology, 2021 Tuberous sclerosis complex (TSC) is an autosomal dominant hereditary disease with hamartomatous growths in multiple organs due to loss-of-function variants in TSC1 or TSC2. In approximately 15% of patients with clinical TSC, no pathogenic variant can be
Eckart Haneke Eckart Haneke
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Protective Barriers Provided by the Epidermis
International Journal of Molecular Sciences, 2023 The skin is the largest organ of the body and consists of an epidermis, dermis and subcutaneous adipose tissue. The skin surface area is often stated to be about 1.8 to 2 m2 and represents our interface with the environment; however, when one considers ...
Sarah de Szalay, P. Wertz
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Single cell transcriptomics of human epidermis identifies basal stem cell transition states
Nature Communications, 2020 How stem cells give rise to epidermis is unclear despite the crucial role the epidermis plays in barrier and appendage formation. Here we use single cell-RNA sequencing to interrogate basal stem cell heterogeneity of human interfollicular epidermis and ...
Shuxiong Wang +11 more
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Frontiers in Plant Science, 2021 Moderate curling generally causes upright leaf blades, which favors the establishment of ideal plant architecture and increases the photosynthetic efficiency of the population, both of which are desirable traits for super hybrid rice (Oryza sativa L ...
Xiaobo Zhang +10 more
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Plants, 2022 In order to understand how and what structures of the tomato ovule with a single integument form the seed coat of a mature seed, a detailed study of the main development stages of the tomato ovule integument was carried out using the methods of light and
Inna A. Chaban +4 more
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Aquaporin-3 in the Epidermis: More than Skin Deep.
American Journal of Physiology - Cell Physiology, 2020 The skin is essential for terrestrial life. It is responsible for regulating water permeability and functions as a mechanical barrier that protects against environmental insults, such as microbial infection, ultraviolet light, injury and heat and cold ...
W. Bollag +3 more
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Plants, 2021 Understanding the mechanisms involved in host plant resistance opens the way for improved resistance breeding programs by using the traits involved as markers. Pest management is a major problem in cultivation of ornamentals.
Dinar S. C. Wahyuni +3 more
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The epidermis coordinates thermoresponsive growth through the phyB-PIF4-auxin pathway
Nature Communications, 2020 In plants, an elevation in ambient temperature induces adaptive morphological changes including elongated hypocotyls, which is predominantly regulated by a bHLH transcription factor, PIF4.
Sara R Kim +9 more
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Chemical & Engineering News Archive, 2007 AbstractThe epidermis is the external surface of an animal and performs several functions. It is usually a monolayer of cells, but can also be composed of several layers of cells. Epidermal cells are connected by cellular junctions (anchoring, occluding, and gap junctions), which are of particular phylogenetic importance.
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