Results 21 to 30 of about 353,568 (296)

UV Radiation and Its Relation to DNA Methylation in Epidermal Cells: A Review

Epigenomes, 2020
DNA methylation is the most studied epigenetic mark, and it can be altered by environmental factors. Among these factors, ultraviolet radiation (UV) is little explored within this context.
Naila Francis Paulo de Oliveira, Beatriz Fernandes de Souza, Marina de Castro Coêlho   +2 more
doaj   +1 more source

An Anhydrous Sodium Chloride Skin Preservation Model for Studies on Keratinocytes Grafting into the Wounds

Pharmaceutics, 2021
Background. Human skin is needed for covering large body areas lost by trauma. The shortcomings of contemporary methods of skin storage are limited preservation time and high immunogenicity if allogeneic. Methods.
Anna Domaszewska-Szostek, Magdalena Gewartowska, Marek Stanczyk, Beata Narowska, Maria Moscicka-Wesołowska, Waldemar Lech Olszewski   +5 more
doaj   +1 more source

Determination of biosorption mechanism in biomass of agave, using spectroscopic and microscopic techniques for the purification of contaminated water [PDF]

, 2019
[Abstract] Lead (Pb2+) and copper (Cu2+) are polluting metals due to their toxicity; however, the extraction of these metals is essential for economic development, so it is important to look for efficient and low-cost alternatives that can remove heavy ...
Barriada, José Luis, Chanona-Pérez, Jorge, Hernández-Botello, M. T., López-Cortez, M. S., Mendoza-Pérez, Jorge Alberto, Sastre de Vicente, Manuel, Téllez-Medina, D. I.   +6 more
core   +1 more source

Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling

eLife, 2018
The first point of our body’s contact with tactile stimuli (innocuous and noxious) is the epidermis, the outermost layer of skin that is largely composed of keratinocytes.
Francie Moehring, Ashley M Cowie, Anthony D Menzel, Andy D Weyer, Michael Grzybowski, Thiago Arzua, Aron M Geurts, Oleg Palygin, Cheryl L Stucky   +8 more
doaj   +1 more source

The use of heat and chemical penetration enhancers to increase the follicular delivery of erythromycin to the skin [PDF]

, 2019
Copyright © 2019. Published by Elsevier B.V.The effect of heat on the follicular absorption of drugs into the skin has not previously been investigated.
Akomeah, Alberti, Baden, Butcher, Cada, Coldman, Edwards, F. Caserta, FDA, Feldmann, Goh, Higuchi, ICH, Q2(R1), Kim, Kligman, Liu, M.B. Brown, McAuley, McAuley, Minson, Motwani, Motwani, OECD, Oliveira, Otberg, Park, Piazza, Pierard, Rancan, Saar, Santos, Sato, Shergill, Szabo, Teichmann, Toll, Twist, W.J. McAuley, Wood, Wood, Wood, Yarnitsky, Zhang   +42 more
core   +2 more sources

Circadian control of interferon-sensitive gene expression in murine skin. [PDF]

, 2020
The circadian clock coordinates a variety of immune responses with signals from the external environment to promote survival. We investigated the potential reciprocal relationship between the circadian clock and skin inflammation.
Andersen, Bogi, Dragan, Morgan, Greenberg, Elyse Noelani, Gudjonsson, Johann E, Jin, Suoqin, Marshall, Michaela Ellen, Nie, Qing, Takahashi, Joseph S, Tsoi, Lam C, Venkatesh, Sanan   +9 more
core   +2 more sources

A protein phosphatase network controls the temporal and spatial dynamics of differentiation commitment in human epidermis

eLife, 2017
Epidermal homeostasis depends on a balance between stem cell renewal and terminal differentiation. The transition between the two cell states, termed commitment, is poorly understood.
Ajay Mishra, Bénédicte Oulès, Angela Oliveira Pisco, Tony Ly, Kifayathullah Liakath-Ali, Gernot Walko, Priyalakshmi Viswanathan, Matthieu Tihy, Jagdeesh Nijjher, Sara-Jane Dunn, Angus I Lamond, Fiona M Watt   +11 more
doaj   +1 more source

Iron Metabolism of the Skin: Recycling versus Release

Metabolites, 2023
The skin protects the body against exogenous stressors. Its function is partially achieved by the permanent regeneration of the epidermis, which requires high metabolic activity and the shedding of superficial cells, leading to the loss of metabolites ...
Marta Surbek, Supawadee Sukseree, Leopold Eckhart   +2 more
doaj   +1 more source

Real-time imaging of pulvinus bending in Mimosa pudica [PDF]

, 2019
Mimosa pudica is a plant that rapidly shrinks its body in response to external stimuli. M. pudica does not perform merely simple movements, but exhibits a variety of movements that quickly change depending on the type of stimuli.
Lee, SJ, Song, K, Yeom, E
core   +1 more source

Keratin 14-dependent disulfides regulate epidermal homeostasis and barrier function via 14-3-3σ and YAP1

eLife, 2020
The intermediate filament protein keratin 14 (K14) provides vital structural support in basal keratinocytes of epidermis. Recent studies evidenced a role for K14-dependent disulfide bonding in the organization and dynamics of keratin IFs in skin ...
Yajuan Guo, Catherine J Redmond, Krystynne A Leacock, Margarita V Brovkina, Suyun Ji, Vinod Jaskula-Ranga, Pierre A Coulombe   +6 more
doaj   +1 more source