Results 11 to 20 of about 253,312 (306)
Protective Barriers Provided by the Epidermis
International Journal of Molecular Sciences, 2023 The skin is the largest organ of the body and consists of an epidermis, dermis and subcutaneous adipose tissue. The skin surface area is often stated to be about 1.8 to 2 m2 and represents our interface with the environment; however, when one considers ...
Sarah de Szalay, P. Wertz
semanticscholar +1 more source
Skin Epidermis and Barrier Function
International Journal of Molecular Sciences, 2021 The skin epidermis is the outermost epithelial tissue that protects the body from the external environment [...].
Kyung-Min Lim
semanticscholar +1 more source
Single cell transcriptomics of human epidermis identifies basal stem cell transition states
Nature Communications, 2020 How stem cells give rise to epidermis is unclear despite the crucial role the epidermis plays in barrier and appendage formation. Here we use single cell-RNA sequencing to interrogate basal stem cell heterogeneity of human interfollicular epidermis and ...
Shuxiong Wang +11 more
semanticscholar +1 more source
Aquaporin-3 in the Epidermis: More than Skin Deep.
American Journal of Physiology - Cell Physiology, 2020 The skin is essential for terrestrial life. It is responsible for regulating water permeability and functions as a mechanical barrier that protects against environmental insults, such as microbial infection, ultraviolet light, injury and heat and cold ...
W. Bollag +3 more
semanticscholar +1 more source
The epidermis coordinates thermoresponsive growth through the phyB-PIF4-auxin pathway
Nature Communications, 2020 In plants, an elevation in ambient temperature induces adaptive morphological changes including elongated hypocotyls, which is predominantly regulated by a bHLH transcription factor, PIF4.
Sara Kim +9 more
semanticscholar +1 more source
Regeneration of the entire human epidermis by transgenic stem cells
Nature, 2017 Junctional epidermolysis bullosa (JEB) is a severe and often lethal genetic disease caused by mutations in genes encoding the basement membrane component laminin-332. Surviving patients with JEB develop chronic wounds to the skin and mucosa, which impair
T. Hirsch +25 more
semanticscholar +1 more source
Defining stem cell dynamics and migration during wound healing in mouse skin epidermis
Nature Communications, 2017 Wound healing is essential to repair the skin after injury. In the epidermis, distinct stem cells (SCs) populations contribute to wound healing. However, how SCs balance proliferation, differentiation and migration to repair a wound remains poorly ...
M. Aragona +6 more
semanticscholar +1 more source
MORPHOLOGICAL PARAMETERS OF SKIN OF PREGNANT EWES OF TUSHIN BREED AT DIFFERENT LEVELS OF FEEDING [PDF]
Volga Region Farmland, 2020 To establish the optimal amount of nutrients in the diets required for the pregnant sheep, in the conditions of the distant-mountain keeping of the North Caucasus in 2018, after tupping, 120 Tushin ewes were selected for the third lambing, which were ...
O.K. Gogaev +2 more
doaj +1 more source
Acta Pharmaceutica, 2021 Ultraviolet B (UVB) induces morphological and functional changes of the skin. This study investigated the effect of UVB on keratinocyte senescence and the development of reconstructed human epidermis (RHE).
Wattanapitayakul Suvara K. +2 more
doaj +1 more source
Dsg2 Upregulation as a Rescue Mechanism in Pemphigus
Frontiers in Immunology, 2020 In pemphigus vulgaris (PV), autoantibodies directed against the desmosomal cadherin desmoglein (Dsg) 3 cause loss of intercellular adhesion. It is known that Dsg3 interactions are directly inhibited by autoantibody binding and that Dsg2 is upregulated in
Anna M. Sigmund +5 more
doaj +1 more source