Results 81 to 90 of about 341,208 (342)

Phospholipase A Activity in the Epidermis

open access: yesJournal of Investigative Dermatology, 1972
Phospholipase A activity has been demonstrated in cow snout epidermis. The activity was higher in the upper layers of the epidermis. The enzyme has been purified by preparing aqueous extracts of acetone powders obtained from epidermal homogenates. The most active preparation gave a pH optimum of 8.3 for the release of free fatty acids from phosphatidyl
V.J.W. Long, H.J. Yardley
openaire   +3 more sources

THE EPIDERMIS AND CYCLIC AMP [PDF]

open access: yesBritish Journal of Dermatology, 1974
Peer Reviewed ; http://deepblue.lib.umich.edu/bitstream/2027.42/73687/1/j.1365-2133.1974.tb06390.x ...
Voorhees, John J., Mier, P. D.
openaire   +4 more sources

Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development [PDF]

open access: yes, 2009
Acquisition of epidermal barrier function occurs late in mouse gestation. Several days before birth a wave of barrier acquisition sweeps across murine fetal skin, converging on dorsal and ventral midlines.
Byrne, C   +3 more
core   +2 more sources

Circadian control of interferon-sensitive gene expression in murine skin. [PDF]

open access: yes, 2020
The circadian clock coordinates a variety of immune responses with signals from the external environment to promote survival. We investigated the potential reciprocal relationship between the circadian clock and skin inflammation.
Andersen, Bogi   +9 more
core   +2 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

open access: yesMolecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau   +9 more
wiley   +1 more source

Morphology and glandular activity of unicellular trichomes of Epilobium hirsutum

open access: yesBiologia Plantarum, 2011
The unusual glandular trichomes of willow-herbs (Epilobium hirsutum L.) were investigated. They are unicellular, without a specialized basal cell at the layer of the epidermis.
S. Strgulc Krajšek   +5 more
doaj   +1 more source

Proteins of Mammalian Epidermis*

open access: yesJournal of Investigative Dermatology, 1955
Epidermis is rather well suited for chemical investigations since it consists of cells derived from a single type, and this tissue is avascular and alymphatic. Histologically epidermis is quite complex since it is characterized by cells representing all stages of differentiation from the basal cells to those which have become completely cornified.
Woernley Dl   +3 more
openaire   +3 more sources

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Catalytic activities of mammalian epoxide hydrolases with cis and trans fatty acid epoxides relevant to skin barrier function

open access: yesJournal of Lipid Research, 2018
Lipoxygenase (LOX)-catalyzed oxidation of the essential fatty acid, linoleate, represents a vital step in construction of the mammalian epidermal permeability barrier.
Haruto Yamanashi   +6 more
doaj   +1 more source

Coral Disease and Health Workshop: Coral Histopathology II [PDF]

open access: yes, 2007
The health and continued existence of coral reef ecosystems are threatened by an increasing array of environmental and anthropogenic impacts. Coral disease is one of the prominent causes of increased mortality among reefs globally, particularly in the ...
Bochsler, V. S.   +14 more
core  

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