Results 111 to 120 of about 576 (142)

Comparison of 3 type VII collagen (C7) assays for serologic diagnosis of epidermolysis bullosa acquisita (EBA)

Journal of the American Academy of Dermatology, 2016
Serologic diagnosis of epidermolysis bullosa acquisita (EBA) relies on the detection of circulating autoantibodies to type VII collagen (C7).We sought to compare the diagnostic performances of a commercialized enzyme-linked immunosorbent assay (ELISA) using C7 noncollagenous (NC) domains (C7-NC1/NC2 ELISA) and indirect immunofluorescence (IIF) biochip ...
Vannina Seta, Françoise Aucouturier, Christelle Le Roux-Villet   +2 more
exaly   +3 more sources

Administration of IgG Fraction of Epidermolysis Bullosa Acquisita (EBA) Serum into Mice

The Journal of Dermatology, 1988
AbstractIn order to study the pathogenic role of autoantibodies in the serum of EBA patients, we tried to induce EBA lesions in mice by administration of the IgG fraction of EBA serum via the intraperitoneal (i.p.) or subcutaneous (s.c.) routes into neonatal or adult mice.
T, Shigemoto, K, Nashiro, T, Tsuchida, Y, Seki, K, Tamaki   +4 more
openaire   +2 more sources

Suppression of experimental epidermolysis bullosa acquisita (EBA) by an IgG monoclonal antibody (mAb) to collagen type VII (COL7)

The Journal of Immunology, 2020
Abstract EBA is a chronic inflammatory, mucocutaneous blistering skin diseases caused by autoantibodies against the structural skin protein, COL7. EBA induction requires autoantibody binding as well as complement- and Fcγ receptor (FcγR)-dependent inflammation.
Unni Krishna Srl Samavedam, Crystal Potter, Elizabeth Angerman, Anika Kasprick, Katja Bieber, Ralf Ludwig, Fred D Finkelman   +6 more
openaire   +1 more source

Manifestation der Epidermolysis bullosa acquisita (EBA) im HNO-Gebiet

HNO, 1999
Epidermolysis bullosa acquisita (EBA) is a rare, chronic, acquired bullous autoimmune dermatosis. It is characterized by the formation of IgG autoantibodies against type VII procollagen of anchoring fibrils with subepidermal formation of bullous lesions and consequent scarring.
M. Bloching, E. Dippel, S. Jovanovic, M. Hess, C. C. Zouboulis   +4 more
openaire   +1 more source

Epidermolysis bullosa acquisita (EBA)

1981
Die EBA-Diagnose stutzt sich auf folgende Kriterien: Das klinische Bild ist dem der Epidermolysis bullosa hereditaria dystrophica recessiva ahnlich. Der hauptsachliche Unterschied ist das Auftreten im reifen Alter sowie eine negative Familienanamnese.
T. Chorzelski, L. Petkow, J. Dąbrowski, T. Krainska, J. Sulej, S. Jablonska, E. H. Beutner   +6 more
openaire   +1 more source

Epidermolysis bullosa acquisita (EBA), eine Fallbeschreibung

1994
Die Epidermolysis bullosa acquisita (EBA) gehort zu den chronischen, blasenbildenden Dermatosen. Nach heutigen Erkenntnissen ist die EBA zu den Autoimmunerkrankungen zu zahlen.
M. Bloching, S. Jovanovic, M. Hess, M. Owsianowski   +3 more
openaire   +1 more source

[Manifestation of epidermolysis bullosa acquisita (EBA) in the ENT area].

HNO, 1999
Epidermolysis bullosa acquisita (EBA) is a rare, chronic, acquired bullous autoimmune dermatosis. It is characterized by the formation of IgG autoantibodies against type VII procollagen of anchoring fibrils with subepidermal formation of bullous lesions and consequent scarring.
M, Bloching, E, Dippel, S, Jovanovic, M, Hess, C C, Zouboulis   +4 more
openaire   +1 more source

Epidermolysis bullosa acquisita (EBA) and esophageal webs: a new association.

The American journal of gastroenterology, 1991
Epidermolysis bullosa acquisita (EBA) is a well-defined, blistering disorder of the skin associated with autoantibodies to type VII collagen. Although esophageal pathology is common in children with hereditary dystrophic forms of epidermolysis bullosa, esophageal problems have not been reported previously in patients with bona fide EBA. In this report,
D, Weinman, M I, Stewart, D T, Woodley, G, Garcia   +3 more
openaire   +1 more source

[Epidermolysis bullosa acquisita (EBA). Morphological, immunocytochemical, optical and ultrastructural study about one case (author's transl)].

Annales de pathologie, 1982
Epidermolysis bullosa acquisita (EBA) is a rare non hereditary bullous disease. One case is described with a morphological, and immunocytochemical ultrastructural study. The plain ultrastructural morphology showed a dense amorphous deposit in the superficial dermis, under the basal lamina. Immunofluorescence showed IgG and C3 deposits.
J, Wechsler, V, Tricottet, F, Capron, M, Galtier, Y, de Prost, M, Reynes   +5 more
openaire   +1 more source

Drug repurposing as a successful principle to identify drugs that alleviate experimental epidermolysis bullosa acquisita (EBA)

2018
Epidermolysis bullosa acquisita (EBA) is a prototypic immunobullous disorder caused by autoantibodies directed against type VII collagen (COL7), which is the major component of the anchoring fibrils at the dermal epidermal junction. Treatment of EBA is difficult and more specifically relies on general immunosuppression.
Ghorbanalipoor, S., Veldkamp, W., Matsumoto, K., Bieber, K., Vidarsson, G., Gupta, Y., Kuenzel, S., Schwaninger, M., Kalies, K., Ludwig, R.   +9 more
openaire   +1 more source