Results 101 to 110 of about 20,159 (200)

The Green Tea Polyphenol Epigallocatechin-Gallate (EGCG) Interferes with Microcin E492 Amyloid Formation. [PDF]

Molecules, 2023
Aguilera P, Berríos-Pastén C, Veloso M, Gálvez-Silva M, Turbant F, Lagos R, Wien F, Arluison V, Marcoleta AE.   +8 more
europepmc   +1 more source

Potentially Toxic Elements and Male Reproductive Toxicity: Mechanisms, Implications, and Protective Strategies: A Narrative Review

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 10, October 2026.
Potentially toxic elements impair male reproductive function through oxidative stress, DNA damage, mitochondrial dysfunction, inflammation, endocrine disruption and epigenetic alterations. Antioxidants, phytochemicals, chelating agents and healthy lifestyle interventions may help mitigate testicular toxicity and preserve fertility.
Sakshi Yadav, Placheril J John
wiley   +1 more source

Integrated phytochemical and bioactivity profiling of Xanthium strumarium fruits from Korea and China: Implications for origin‐specific quality specification

Journal of the Science of Food and Agriculture, Volume 106, Issue 13, Page 7606-7613, October 2026.
Abstract BACKGROUND Geographic origin influences the phytochemical composition and biological activities of medicinal plant resources. Xanthium strumarium L. (XS) fruit is widely used in East Asian traditional medicine. However, current pharmacopeial standards primarily recognize Chinese‐derived material, despite the availability and traditional use of
Eunsu Song, Seung‐Min Oh, Jiyeon Chun, Jinah Hwang   +3 more
wiley   +1 more source

Dual Antiviral and Immunomodulatory Effects of Phytochemicals in Influenza A Virus Infection: Targeting Key Host Signaling Pathways

MicrobiologyOpen, Volume 15, Issue 5, October 2026.
Influenza A virus modulates host innate immune pathways, including TLR, RIG‐I, MAPK, and NF‐κB signaling, to support replication and drive inflammatory pathology. Plant‐derived phytocompounds target these interconnected pathways, offering a potential host‐directed immunomodulatory approach complementary to conventional antivirals.
Dibakar Chowdhury, Hillary A. Vanderven, Phurpa Wangchuk, Subir Sarker   +3 more
wiley   +1 more source

Advanced Glycation End Products: From Pathogenesis to Treatment

MedComm, Volume 7, Issue 10, October 2026.
Therapeutic landscape of AGE‐targeted intervention. Schematic representation of intervention strategies targeting distinct stages of AGE biology. Upstream prevention aims to reduce exposure and formation through low‐AGE cooking, smoking cessation, glycemic control, and metabolic optimization.
Tak‐Ho Lo, Junying Zou, Jingyi Zhang, Kaijun Lin, Minhui Zhu, Shuangqi Lu, Xin Liu, Mengyao Wu   +7 more
wiley   +1 more source

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges

Phytotherapy Research, Volume 40, Issue 10, Page 5973-5987, October 2026.
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, is aggressive and often diagnosed late, making treatment challenging. This review highlights the potential of phytochemicals, such as curcumin and quercetin, as multitarget agents that influence key carcinogenic pathways. These compounds exhibit anticancer effects by inhibiting processes
Md. Rezaul Islam, Abdur Rauf, F. M. Shourav, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Kamala Badalova, Marcello Iriti   +7 more
wiley   +1 more source

Ultrasound-assisted free radical modification on the structural and functional properties of ovalbumin-epigallocatechin gallate (EGCG) conjugates. [PDF]

Ultrason Sonochem, 2023
Zheng Y, Chen B, Huang X, Teng H, Ai C, Chen L.   +5 more
europepmc   +1 more source

Novel Flavonoid Senotherapeutics Identified by Phenotypic Drug Discovery Reduce Senescence and Improve Multiple Markers of Healthspan

Aging Cell, Volume 25, Issue 10, October 2026.
Phenotypic screening and SAR‐guided drug design identified two flavonoid‐derived senolytics, SR29384 and SR31133, which selectively killed different types of senescent cells more efficiently and with greater selectivity than fisetin in culture. In aged and progeroid mice, these fisetin analogs reduced tissue senescence and improved physical function ...
Lei Justan Zhang, Rahagir Salekeen, Carolina Soto‐Palma, Qiuming Wu, Yuanjun He, Osama Elsallabi, Bilel Bdiri, Brian Hughes, Allancer Nunes, Wandi Xu, Borui Zhang, Abdalla Mohamed, Sara J. McGowan, Luise Angelini, Ryan O'Kelly, Theodore M. Kamenecka, Laura J. Niedernhofer, Paul D. Robbins   +17 more
wiley   +1 more source

The evaluation of catechins reducing heterocyclic aromatic amine formation: Structure-activity relationship and mechanism speculation

Current Research in Food Science
The favorable inhibitory effect of tea polyphenols on heterocyclic aromatic amines (HAAs) has been confirmed in many past studies. The objective of this study was to investigate the structure-activity relationship of catechins that act as inhibitors of ...
Ruiwei Xie, Haolin Zhang, Xiaomei Lv, Qiuyi Lin, Bing-Huei Chen, Yu-Wen Lai, Lei Chen, Hui Teng, Hui Cao   +8 more
doaj   +1 more source

In vitro biological evaluation of epigallocatechin gallate (EGCG) release from three-dimensional printed (3DP) calcium phosphate bone scaffolds. [PDF]

J Mater Chem B, 2023
Jo Y, Sarkar N, Bose S.
europepmc   +1 more source