Results 111 to 120 of about 20,159 (200)

The Skin‐Lightening Efficacy and Mechanisms of Botanical Extracts: A Comprehensive Review

Journal of Cosmetic Dermatology, Volume 25, Issue 10, October 2026.
ABSTRACT Background Skin pigmentation is regulated by a complex network involving melanogenesis, melanosome transfer, oxidative stress, environmental stimuli, and epidermal turnover. Botanical extracts and phytochemicals have attracted increasing interest as potential skin‐lightening agents. This review evaluates their efficacy, mechanisms, and safety.
Siting Yang, Mingning Ding, Chenglong Ye, Jingning Shen, Lihua Zhang, Anquan Yang, Lihao Gu   +6 more
wiley   +1 more source

Efficacy and safety of 7-day aerosolized epigallocatechin-3-gallate in oncologic patients with COVID-19 pneumonia

BMC Cancer
Background Oncologic patients are vulnerable to prolonged or severe COVID-19 due to immunosuppression and comorbidities. Our initial Phase I/II clinical trial has showed​ that epigallocatechin-3-gallate (EGCG), a catechin monomer isolated from tea ...
Wanqi Zhu, Li Jia, Qiang Qiao, Xiaolin Li, Xie Peng, Xiangjiao Meng, Lingling Kong, Hanxi Zhao   +7 more
doaj   +1 more source

The Potential of Epigallocatechin Gallate (EGCG) in Targeting Autophagy for Cancer Treatment: A Narrative Review. [PDF]

Int J Mol Sci, 2022
Ferrari E, Bettuzzi S, Naponelli V.
europepmc   +1 more source

E3 Ubiquitin Ligases in MASH‐Associated Liver Fibrosis: Mechanisms and Therapeutic Opportunities

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Metabolic dysfunction‐associated steatohepatitis (MASH) is a major cause of progressive liver fibrosis and can ultimately lead to cirrhosis and hepatocellular carcinoma (HCC). MASH‐associated liver fibrosis develops through a complex interplay among lipotoxic hepatocyte injury, oxidative and endoplasmic reticulum stress, inflammatory ...
Ah‐Reum Oh, Yelin Jeong, Young Hoon Jung, Young Un Kim, HyunJoon Gi, Do‐Wan Kim, Young Du Choi, Sang Bae Lee, KyeongJin Kim   +8 more
wiley   +1 more source

Epigallocatechin gallate (EGCG) alleviates vascular dysfunction in angiotensin II-infused hypertensive mice by modulating oxidative stress and eNOS. [PDF]

Sci Rep, 2022
Mohd Sabri NA, Lee SK, Murugan DD, Ling WC.   +3 more
europepmc   +1 more source

A novel CsRNF‐CsHSF24‐CsF3′5′H2 module regulates epigallocatechin gallate biosynthesis in Camellia sinensis

The Plant Journal, Volume 128, Issue 1, October 2026.
Significance Statement While the biosynthetic pathway of tea catechins is well established, how post‐translational modifications govern this process has remained elusive. This study uncovers a regulatory module in which the E3 ubiquitin ligase CsRNF targets the transcription factor CsHSF24 for degradation, thereby controlling expression of the key ...
Xinzhuan Yao, Hufang Chen, Haili An, Yilan Hu, Tong Li, Qi Zhao, Tengxian He, Chao Luo, Xiaofang Zeng, Litang Lu   +9 more
wiley   +1 more source

Polyurethane Nanocapsules Incorporating Epigallocatechin Gallate, A Green Tea Extract

Advanced NanoBiomed Research
Explosions cause 79% of combat‐related injuries, often leading to traumatic brain injury (TBI) and hemorrhage. Epigallocatechin gallate (EGCG), a green tea polyphenol, aids neuroprotection and wound healing.
Temitope Ale, Nhyira Ghunney, Narendra Pandala, Budd Tucker, Kassandra McFadden, Jack Hutcheson, Erin Lavik   +6 more
doaj   +1 more source

Epigallocatechin Gallate (EGCG), a Green Tea Polyphenol, Reduces Coronavirus Replication in a Mouse Model. [PDF]

Viruses, 2021
Park R, Jang M, Park YI, Park Y, Jung W, Park J, Park J.   +6 more
europepmc   +1 more source

Safety of frozen paste from blanched, whole migratory locust (Locusta migratoria) as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Journal, Volume 24, Issue 10, October 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on frozen paste from blanched, whole migratory locusts (Locusta migratoria) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is produced from farmed sub‐adult L. migratoria, which
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Montaña Cámara, Jacqueline Castenmiller, Stefaan De Henauw, Ángeles Jos, Alexandre Maciuk, Inge Mangelsdorf, Breige McNulty, Androniki Naska, Kristina Pentieva, Alfonso Siani, Frank Thies, Margarita Aguilera Gomez, Thomas Frenzel, Francesca Marcon, Harry McArdle, Peter Moldeus, Monika Neuhäuser Berthol, Salvatore Multari, Domenico Azzollini, Karen Ildico Hirsch‐Ernst   +23 more
wiley   +1 more source

Epigallocatechin Gallate (EGCG), an Active Phenolic Compound of Green Tea, Inhibits Tumor Growth of Head and Neck Cancer Cells by Targeting DNA Hypermethylation. [PDF]

Biomedicines, 2023
Agarwal A, Kansal V, Farooqi H, Prasad R, Singh VK.   +4 more
europepmc   +1 more source