Results 71 to 80 of about 20,159 (200)

Effects of Green Tea Supplementation on Chemoprevention at Different Stages of Carcinogenesis: A Systematic Review

Phytotherapy Research, EarlyView.
ABSTRACT Green tea catechins have chemopreventive potential; however, the clinical evidence remains inconsistent. This review evaluated the effects of supplementation with green tea derivatives on chemoprevention at different stages of carcinogenesis. PubMed, Embase, Web of Science, Scopus, the Cochrane Library, CINAHL, and Google Scholar were searched
Thaís Moreira Machado, Mariene Garcia Gomes, Érika Yuri Hirose Murahara, Ana Lúcia Chalhoub Chediac Rodrigues, Ariane Nadolskis Severine, Thais Giovaninni Roberto, Sinara Laurini Rossato   +6 more
wiley   +1 more source

Protective Effect of Epigallocatechin‐3‐Gallate Against Fructose‐Induced Metabolic Associated Fatty Liver Disease in Mice by Regulating Ferroptosis and Autophagy via SIRT5

Phytotherapy Research, EarlyView.
ABSTRACT Metabolic dysfunction‐associated fatty liver disease (MAFLD) lacks effective pharmacological therapies and is strongly associated with excessive fructose consumption. Ferroptosis and autophagy dysregulation are increasingly recognized as key drivers of MAFLD progression.
Puyu Zhang, Cuiping Hou, Jiayi Liu, Bosheng Wang, Wenqi Liu, Xin Yang, Yubing Kang, Zequn Liu, Yalin Zhang, Zhuxi Liu, Yuhong Zhao, Lu Zhao   +11 more
wiley   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

Responsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang, Xuan Hou, Haiping Zhao, Qi Kong, Xiayan Wang, Xiaokun Geng, Zaicheng Sun   +6 more
wiley   +1 more source

Preparation and Stability of Whey Protein Isolation-high Acyl Gellan Gum Nanoparticles Loaded with EGCG

Liang you shipin ke-ji
In this paper, the whey protein isolate (WPI) and gellan gum (GG) nanocomposites (WPI-GG) were prepared by ultrasonic treatment. Epigallocatechin-3-gallate (EGCG) was loaded through non-covalent interaction and the stability of EGCG was enhanced.
ZHU Meng-lu, ZHOU Xin, LI Jing, GUO Na, ZHU Gui-lan   +4 more
doaj   +1 more source

Monodisperse Condensed Tannin and Derived Carbon Nanospheres Featuring Well‐Defined Surface‐Structured Metal Species

Small, EarlyView.
Uniform, size‐tunable polyphenol nanospheres are assembled from condensed tannins in water at ambient conditions via controlled supramolecular interactions between tannin and diamines. Their phenolic–amine surfaces template highly dispersed metal species that resist sintering during pyrolysis.
Weitong Wang, Jiaqi Wang, Bin Zhao, Tianyang Wen, Daniel Martín‐Yerga, Monika Österberg, Erlantz Lizundia, Bruno D. Mattos   +7 more
wiley   +1 more source

Effect of Phenolic Hydroxyl Group Number on Regulation of the Self-Assembly Behavior of Edible Dock Protein and Catechins

Foods
To investigate the effect of phenolic hydroxyl group number on the interaction between catechins and a plant-derived protein carrier, four catechins with varying hydroxyl numbers—epicatechin (EC), epicatechin gallate (ECG), epigallocatechin (EGC), and ...
Hao Ma, Shandan Zhao, Chenchen Wang, Yajun Lin, Kang Liu   +4 more
doaj   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

VIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang, Junlei Chai, Quanwei Ding, Luping Liu, Kejie Zhang, Jie Lin, Jianhua Zhang, Youju Huang   +7 more
wiley   +1 more source

Computational and Biochemical Discovery of RSK2 as a Novel Target for Epigallocatechin Gallate (EGCG)

PLOS ONE, 2015
The most active anticancer component in green tea is epigallocatechin-3-gallate (EGCG). Protein interaction with EGCG is a critical step for mediating the effects of EGCG on the regulation of various key molecules involved in signal transduction.
Hanyong Chen, Ke Yao, Xiaoyu Chang, Jung-Hyun Shim, Hong-Gyum Kim, Margarita Malakhova, Dong-Joon Kim, Ann M Bode, Zigang Dong   +8 more
openaire   +4 more sources

Oxidized epigallocatechin gallate inhibited lysozyme fibrillation more strongly than the native form

Redox Biology, 2017
Epigallocatechin gallate (EGCG), the most abundant flavanoid in green tea, is currently being evaluated in the clinic due to its benefits in the treatment of amyloid disorders.
Ting-Ting An, Shuang Feng, Cheng-Ming Zeng   +2 more
doaj   +1 more source

Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges

British Journal of Pharmacology, EarlyView.
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu, Kaibin Dai, Zhensheng Lin, Mingfang Ye, Minfeng Chen, Xiaobo Li, Dongmei Zhang   +6 more
wiley   +1 more source