Results 11 to 20 of about 2,699,284 (182)

Epigenetic Modulation of IL-7 and IL-10: Toward Personalized Immune Therapies in Viral Epidemics. [PDF]

open access: yesJ Immunol Res
Background Host immune responses, including cytokine production, shape the severity of viral epidemics. Epigenetic mechanisms such as DNA methylation regulate cytokine gene expression and may contribute to immune dysregulation in severe disease. Methods This study analyzed interleukin‐7 (IL‐7), IL‐8, and IL‐10 promoter methylation in 145 COVID‐19 ...
Yulugkural Z   +4 more
europepmc   +2 more sources

Valproic acid and bladder healing: an experimental study in rats

open access: yesRevista do Colégio Brasileiro de Cirurgiões, 2022
Purpose: to recognize the effects of valproic acid (VPA), an epigenetic drug, on the bladder healing process, in rats. Method: twenty male Wistar rats were divided in two groups: experimental (A), treated with VPA (150mg/Kg/day), and control (B) with ...
MARIA DE LOURDES PESSOLE BIONDO-SIMÕES   +5 more
doaj   +2 more sources

Epigenetic regulation in lung cancer

open access: yesMedComm, Volume 4, Issue 6, December 2023., 2023
Role of epigenetics in lung cancer. Epigenetics is considered the main cause of lung cancer. Epigenetics is categorized into three phenomena: histone modification, DNA methylation, and noncoding RNAs. One of the main approaches to controlling lung cancer is early diagnosis.
Shahin Ramazi   +3 more
wiley   +1 more source

The females' response to male attractiveness: Mate choice, larvae production and differential brain protein expression

open access: yesEthology, Volume 129, Issue 10, Page 515-526, October 2023., 2023
Our study in Tenebrio molitor employed behavioral and proteomic analyses to establish a correlation between female mate choice and molecular changes in the female brain. We found that females preferred mating with more attractive males, who in turn had a greater likelihood of successfully mating and producing more larvae with attractive males than with
Miguel Hernández‐Villanueva   +3 more
wiley   +1 more source

Patterns of Reliability: Assessing the Reproducibility and Integrity of DNA Methylation Measurement

open access: yesPatterns, 2020
Summary: DNA methylation plays an important role in both normal human development and risk of disease. The most utilized method of assessing DNA methylation uses BeadChips, generating an epigenome-wide “snapshot” of >450,000 observations (probe ...
Karen Sugden   +15 more
doaj   +1 more source

Themes of trust, identity, intimacy, and generativity in important autobiographical memories: Associations with life periods and life satisfaction

open access: yesJournal of Personality, Volume 91, Issue 5, Page 1110-1122, October 2023., 2023
Abstract Introduction Guided by Erikson's theory of psychosocial development, the present study investigated whether themes of trust, identity, intimacy, and generativity are represented in older adults' most important autobiographical memories. Furthermore, we tested whether these themes are associated with certain life periods and whether having ...
Lisa Nusser, Daniel Zimprich, Tabea Wolf
wiley   +1 more source

Evolutionary ecology of the North Atlantic Talitridae (Crustacea, Amphipoda): A review [PDF]

open access: yesZoosystematics and Evolution
Four primary estuarine/marine ecotopes recognized in the North Atlantic continental littoral and continental terrestrial margins give rise to the following ecotypes: wrack generalists (=beach-hoppers), psammophilic talitrids (=sandburrowing-hoppers ...
David J. Wildish
doaj   +3 more sources

The modern versus extended evolutionary synthesis : sketch of an intra-genomic gene's eye view for the evolutionary-genetic underpinning of epigenetic and developmental evolution [PDF]

open access: yes, 2018
Studying the phenotypic evolution of organisms in terms of populations of genes and genotypes, the Modern Synthesis (MS) conceptualizes biological evolution in terms of 'inter-organismal' interactions among genes sitting in the different individual ...
Blancke, Stefaan   +2 more
core   +3 more sources

In vitro culture of reptile PGCS to preserve endangered species

open access: yesCell Biology International, Volume 47, Issue 8, Page 1314-1326, August 2023., 2023
Abstract Primordial germ cells (PGCs), are the source of gametes in vertebrates. There are similarities in the development of PGCs of reptiles with avian and mammalian species PGCs development. PGCs culture has been performed for avian and mammalian species but there is no report for reptilian PGCs culture. In vitro culture of PGCs is needed to produce
Afsaneh Golkar‐Narenji   +5 more
wiley   +1 more source

Promoter DNA Methylation Frequency and Clinicopathological Role of miR-129-2 Gene in Patients with Chronic Lymphocytic Leukemia

open access: yesOman Medical Journal, 2020
Objectives: Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of apparently mature B-type lymphocytes in the lymphohematopoietic organs.
Morteza Hashemi   +3 more
doaj   +1 more source

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