Results 21 to 30 of about 2,699,284 (182)

Epigenetic DNA changes and stem cells therapy [PDF]

Archive of Oncology, 2013
We are starting to understand the fundamental biological processes which underlie the DNA physical properties. Of particular importance is the field of epigenetics, which literally means 'outside conventional genetics', now used to describe the study ...
Stupar Milanko, Vidović Vitomir, Baltić Vladimir, Štrbac Ljuba, Lukač Dragomir   +4 more
doaj   +1 more source

Quercetin as an Emerging Anti-Melanoma Agent: A four-focus area therapeutic development strategy

Frontiers in Nutrition, 2016
Replacing current refractory treatments for melanoma with new prevention and therapeutic approaches is crucial in order to successfully treat this aggressive cancer form. Melanoma develops from neural crest cells, which express tyrosinase -- a key enzyme
Zoey Harris, Micah G. Donovan, Gisele Morais Branco, Kirsten Limesand, Randy Burd   +4 more
doaj   +1 more source

Association Between <i>rs920778</i> Polymorphisms and Cancer Risk: An Updated Meta-Analysis. [PDF]

Genet Res (Camb)
Background: A growing number of studies are exploring the association between HOTAIR rs920778 polymorphisms and cancer risk, but to date, there has been controversy and uncertainty. Preliminary evidence suggests that this polymorphism may influence cancer susceptibility, particularly in Asian populations and specific cancer types such as cervical ...
Xu L, Deng J, Gong L, Chen Y, Hu G.
europepmc   +2 more sources

Biological Information, Causality and Specificity - an Intimate Relationship [PDF]

, 2017
In this chapter we examine the relationship between biological information, the key biological concept of specificity, and recent philosophical work on causation.
Griffiths, Paul E., Stotz, Karola
core   +2 more sources

Juvenile methylphenidate reduces prefrontal cortex plasticity via D3 receptor and BDNF in adulthood

Frontiers in Synaptic Neuroscience, 2014
Background: Early drug intervention in childhood disorders aims to maximize individual potential in the short- and long-term. Consistently, juvenile exposure to psychostimulants, such as methylphenidate (MPH), reduces risk for substance use in animals ...
Susan L Andersen, Kai Christian Sonntag
doaj   +1 more source

Extending Epigenesis: From Phenotypic Plasticity to the Bio-Cultural Feedback [PDF]

, 2017
The paper aims at proposing an extended notion of epigenesis acknowledging an actual causal import to the phenotypic dimension for the evolutionary diversification of life forms.
A Bouaïchi, A Pascual-Leone, A Petronis, A Probst, A Wagner, AD Goldberg, AP Moczek, B Draganski, B Draganski, B Draganski, B Hrvoj-Mihic, C Dupont, CD Allis, CD Schlichting, CH Darwin, CH Darwin, CH Waddington, CH Waddington, CH Waddington, D Amati, D Bickerton, D Stout, D Stout, D Vazquez-Sanroman, DH Ho, DJ Bolger, DJ Cove, E Jablonka, E Jablonka, E Jablonka, E Saló, EE Hecht, EJ Richards, F Calabrese, F Lui, F Lyco, F Vinckier, G Auletta, G Auletta, G Auletta, G Fusco, G Jobard, G Manzi, G Schlosser, G Tononi, GB Müller, GH Tang, GM Edelman, H Gintis, H Ishibashi, H Vries de, I Colagè, I Colagè, I Colagè, I Colagè, I Colagè, ICG Weaver, ICG Weaver, II Schmalhausen, Ivan Colagè, J Caspers, J Masel, J Sapp, J Sapp, J Varrela, J Varrela, J-P Changeux, JD Yeatman, JK Rilling, JM Whitacre, JP Collins, JW Lewis, K Schick, K Woollett, KD Walton, KN Laland, L Caspers, L Cohen, L Daxinger, L Reich, LV Hooper, LV Hooper, M Heiser, M Iacoboni, M Iacoboni, M Kirschner, M Pigliucci, M Ptashne, M Sato, M Somel, M Szwed, M Thiebaut de Schotten, M Vigneau, MH Johnson, MH Johnson, MJ West-Eberhard, ML Anderson, ML Anderson, ML Anderson, ML Anderson, P D’Ambrosio, P Hammerstein, Paolo D’Ambrosio, PF Ferrari, PH Mason, PS Murray, R Amundson, R Gaillard, R Liebers, RA Waterland, RM Burian, RS Corruccini, S Crawford-Young, S Dehaene, S Dehaene, S Dehaene, S Hihara, S Oyama, SE Sultan, SF Gilbert, SF Gilbert, SF Gilbert, SF Gilbert, SJ Gould, SJ Gould, SJ Gould, SK Mazmanian, SM Rogers, T Adell, TJH Morgan, W Arthur, WC Wimsatt, WW Burggren, Z Petanjek, ZM Saygin   +134 more
core   +1 more source

The Pathogenesis of Endometriosis: Molecular and Cell Biology Insights

International Journal of Molecular Sciences, 2019
The etiopathogenesis of endometriosis is a multifactorial process resulting in a heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still far from being fully elucidated, the current review aims to offer a comprehensive ...
A. Laganà, S. Garzon, M. Götte, P. Viganò, M. Franchi, F. Ghezzi, D. Martin   +6 more
semanticscholar   +1 more source

A network analysis of crab metamorphosis and the hypothesis of development as a process of unfolding of an intensive complexity

Scientific Reports, 2021
Development has intrigued humanity since ancient times. Today, the main paradigm in developmental biology and evolutionary developmental biology (evo-devo) is the genetic program, in which development is explained by the interplay and interaction of ...
Agustín Ostachuk
doaj   +1 more source

Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults

Clinical Epigenetics, 2019
Background Ambient air pollution is associated with numerous adverse health outcomes, but the underlying mechanisms are not well understood; epigenetic effects including altered DNA methylation could play a role. To evaluate associations of long-term air
Mi Kyeong Lee, Cheng-Jian Xu, Megan U. Carnes, Cody E. Nichols, James M. Ward, The BIOS consortium, Sung Ok Kwon, Sun-Young Kim, Woo Jin Kim, Stephanie J. London   +9 more
doaj   +1 more source

Relationship between the expression level of microRNA and the features of clinical course of the gallbladder and Оddi's sphincter functional disorders in children

Zaporožskij Medicinskij Žurnal, 2019
The aim of the work is to establish the relationship between the expression levels of microRNA-378f, microRNA-4311, microRNA-4714-3p and anamnestic, clinical and paraclinical parameters of functional disorders of the gallbladder and Oddi's sphincter (FD ...
O. Ye. Abaturov, V. L. Babуch
doaj   +1 more source