Results 21 to 30 of about 2,621,371 (204)

Current status of genome‐wide epigenetic profiling of mammalian preimplantation embryos

Reproductive Medicine and Biology, Volume 22, Issue 1, January/December 2023., 2023
Abstract Background Genome‐wide information on epigenetic modifications in mammalian preimplantation embryos was an unexplored sanctuary of valuable research insights protected by the difficulty of its analysis. However, that is no longer the case, and many epigenome maps are now available for sightseeing there.
Shuntaro Ikeda
wiley   +1 more source

The modern versus extended evolutionary synthesis : sketch of an intra-genomic gene's eye view for the evolutionary-genetic underpinning of epigenetic and developmental evolution [PDF]

, 2018
Studying the phenotypic evolution of organisms in terms of populations of genes and genotypes, the Modern Synthesis (MS) conceptualizes biological evolution in terms of 'inter-organismal' interactions among genes sitting in the different individual ...
Blancke, Stefaan, Braeckman, Johan, De Tiège, Alexis   +2 more
core   +3 more sources

Promoter DNA Methylation Frequency and Clinicopathological Role of miR-129-2 Gene in Patients with Chronic Lymphocytic Leukemia

Oman Medical Journal, 2020
Objectives: Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of apparently mature B-type lymphocytes in the lymphohematopoietic organs.
Morteza Hashemi, Mahshid Mohammadipour, Shahrbano Rostami, Mohammad Soleiman Soltanpour   +3 more
doaj   +1 more source

Epigenetic DNA changes and stem cells therapy [PDF]

Archive of Oncology, 2013
We are starting to understand the fundamental biological processes which underlie the DNA physical properties. Of particular importance is the field of epigenetics, which literally means 'outside conventional genetics', now used to describe the study ...
Stupar Milanko, Vidović Vitomir, Baltić Vladimir, Štrbac Ljuba, Lukač Dragomir   +4 more
doaj   +1 more source

Juvenile methylphenidate reduces prefrontal cortex plasticity via D3 receptor and BDNF in adulthood

Frontiers in Synaptic Neuroscience, 2014
Background: Early drug intervention in childhood disorders aims to maximize individual potential in the short- and long-term. Consistently, juvenile exposure to psychostimulants, such as methylphenidate (MPH), reduces risk for substance use in animals ...
Susan L Andersen, Kai Christian Sonntag
doaj   +1 more source

Quercetin as an Emerging Anti-Melanoma Agent: A four-focus area therapeutic development strategy

Frontiers in Nutrition, 2016
Replacing current refractory treatments for melanoma with new prevention and therapeutic approaches is crucial in order to successfully treat this aggressive cancer form. Melanoma develops from neural crest cells, which express tyrosinase -- a key enzyme
Zoey Harris, Micah G. Donovan, Gisele Morais Branco, Kirsten Limesand, Randy Burd   +4 more
doaj   +1 more source

Biological Information, Causality and Specificity - an Intimate Relationship [PDF]

, 2017
In this chapter we examine the relationship between biological information, the key biological concept of specificity, and recent philosophical work on causation.
Griffiths, Paul E., Stotz, Karola
core   +2 more sources

The Pathogenesis of Endometriosis: Molecular and Cell Biology Insights

International Journal of Molecular Sciences, 2019
The etiopathogenesis of endometriosis is a multifactorial process resulting in a heterogeneous disease. Considering that endometriosis etiology and pathogenesis are still far from being fully elucidated, the current review aims to offer a comprehensive ...
A. Laganà, S. Garzon, M. Götte, P. Viganò, M. Franchi, F. Ghezzi, D. Martin   +6 more
semanticscholar   +1 more source

A network analysis of crab metamorphosis and the hypothesis of development as a process of unfolding of an intensive complexity

Scientific Reports, 2021
Development has intrigued humanity since ancient times. Today, the main paradigm in developmental biology and evolutionary developmental biology (evo-devo) is the genetic program, in which development is explained by the interplay and interaction of ...
Agustín Ostachuk
doaj   +1 more source

Extending Epigenesis: From Phenotypic Plasticity to the Bio-Cultural Feedback [PDF]

, 2017
The paper aims at proposing an extended notion of epigenesis acknowledging an actual causal import to the phenotypic dimension for the evolutionary diversification of life forms.
A Bouaïchi, A Pascual-Leone, A Petronis, A Probst, A Wagner, AD Goldberg, AP Moczek, B Draganski, B Draganski, B Draganski, B Hrvoj-Mihic, C Dupont, CD Allis, CD Schlichting, CH Darwin, CH Darwin, CH Waddington, CH Waddington, CH Waddington, D Amati, D Bickerton, D Stout, D Stout, D Vazquez-Sanroman, DH Ho, DJ Bolger, DJ Cove, E Jablonka, E Jablonka, E Jablonka, E Saló, EE Hecht, EJ Richards, F Calabrese, F Lui, F Lyco, F Vinckier, G Auletta, G Auletta, G Auletta, G Fusco, G Jobard, G Manzi, G Schlosser, G Tononi, GB Müller, GH Tang, GM Edelman, H Gintis, H Ishibashi, H Vries de, I Colagè, I Colagè, I Colagè, I Colagè, I Colagè, ICG Weaver, ICG Weaver, II Schmalhausen, Ivan Colagè, J Caspers, J Masel, J Sapp, J Sapp, J Varrela, J Varrela, J-P Changeux, JD Yeatman, JK Rilling, JM Whitacre, JP Collins, JW Lewis, K Schick, K Woollett, KD Walton, KN Laland, L Caspers, L Cohen, L Daxinger, L Reich, LV Hooper, LV Hooper, M Heiser, M Iacoboni, M Iacoboni, M Kirschner, M Pigliucci, M Ptashne, M Sato, M Somel, M Szwed, M Thiebaut de Schotten, M Vigneau, MH Johnson, MH Johnson, MJ West-Eberhard, ML Anderson, ML Anderson, ML Anderson, ML Anderson, P D’Ambrosio, P Hammerstein, Paolo D’Ambrosio, PF Ferrari, PH Mason, PS Murray, R Amundson, R Gaillard, R Liebers, RA Waterland, RM Burian, RS Corruccini, S Crawford-Young, S Dehaene, S Dehaene, S Dehaene, S Hihara, S Oyama, SE Sultan, SF Gilbert, SF Gilbert, SF Gilbert, SF Gilbert, SJ Gould, SJ Gould, SJ Gould, SK Mazmanian, SM Rogers, T Adell, TJH Morgan, W Arthur, WC Wimsatt, WW Burggren, Z Petanjek, ZM Saygin   +134 more
core   +1 more source