Results 41 to 50 of about 43,533 (191)

Genes in the postgenomic era [PDF]

open access: yes, 2006
We outline three very different concepts of the gene - 'instrumental', 'nominal', and 'postgenomic'. The instrumental gene has a critical role in the construction and interpretation of experiments in which the relationship between genotype and phenotype ...
B. Alberts   +38 more
core   +2 more sources

Factors and mechanisms of productive secondary reservoirs formation in deep-lying oil and gas complexes. Article 1. Tectonophysical mechanisms of Lower Carboniferous quartzite-sandstones decompaction in the central part of the Dniprovsko-Donetska depression at the depths of more than 4.5 km

open access: yesМінеральні ресурси України
In the world, the scale of development of secondary reservoirs in decompaction rock bodies in a wide formation range is steadily increasing: from the crystalline basement of different ages of various oil and gas-bearing basins to terrigenous deposits ...
O. Yu. Lukin, I. P. Gafych, Ya. V. Lukin
doaj   +1 more source

A Regression-based Approach to Robust Estimation and Inference for Genetic Covariance [PDF]

open access: yesarXiv, 2021
Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with complex traits, and some variants are shown to be associated with multiple complex traits. Genetic covariance between two traits is defined as the underlying covariance of genetic effects and can be used to measure the shared genetic architecture.
arxiv  

A Scoping Review of Neighborhood Effects and Health Among Children and Adolescents: Measurement and Design Characteristics

open access: yesJournal of Community Psychology, Volume 53, Issue 4, May 2025.
ABSTRACT Decades of research have explored how neighborhood conditions relate to child and adolescent health, spawning numerous reviews focused on specific predictors, outcomes, or populations. Less is known about the design and characteristics underpinning this work.
Bria Gresham, Canan Karatekin
wiley   +1 more source

Crossovers between epigenesis and epigenetics. A multicenter approach to the history of epigenetics (1901-1975) [PDF]

open access: yes, 2014
The origin of epigenetics has been traditionally traced back to Conrad Hal Waddington's foundational work in 1940s. The aim of the present paper is to reveal a hidden history of epigenetics, by means of a multicenter approach.
Costa, R., Frezza, G.
core  

Developmental Systems Theory as a Process Theory [PDF]

open access: yes, 2018
Griffiths and Russell D. Gray (1994, 1997, 2001) have argued that the fundamental unit of analysis in developmental systems theory should be a process – the life cycle – and not a set of developmental resources and interactions between those resources ...
Griffiths, Paul Edmund, Stotz, Karola
core  

An Anaerobic Microbial Community Mediates Epigenetic Native Sulfur and Carbonate Formation During Replacement of Messinian Gypsum at Monte Palco, Sicily

open access: yesGeobiology, Volume 23, Issue 2, March/April 2025.
ABSTRACT The microbially mediated replacement of sulfate‐bearing evaporites by authigenic carbonate and native sulfur under anoxic conditions is poorly understood. Sulfur‐bearing carbonates from the Monte Palco ridge (Sicily) replacing Messinian gypsum were therefore studied to better characterize the involved microorganisms.
Simon E. Rouwendaal   +9 more
wiley   +1 more source

Better living through chemistry: caloric restriction (CR) and CR mimetics alter genome function to promote increased health and lifespan

open access: yesFrontiers in Genetics, 2016
Caloric restriction (CR), defined as decreased nutrient intake without causing malnutrition, has been documented to increase both health and lifespan across numerous organisms, including humans.
Zoe E. Gillespie   +3 more
doaj   +1 more source

Comparison of REML methods for the study of phenome-wide genetic variation [PDF]

open access: yesarXiv, 2022
It is now well documented that genetic covariance between functionally related traits leads to an uneven distribution of genetic variation across multivariate trait combinations, and possibly a large part of phenotype-space that is inaccessible to evolution.
arxiv  

Thinking about the next generation: The case for a mentalization‐informed approach to perinatal and intergenerational mental health

open access: yesPsychology and Psychotherapy: Theory, Research and Practice, Volume 97, Issue S1, Page 1-15, November 2024.
Abstract Background There has been substantial progress made across multiple disciplines to emphasize the importance of perinatal mental health both for parents and offspring. This focuses on what has been termed the ‘First 1000 Days’ from conception to the child's second birthday.
Angus MacBeth   +6 more
wiley   +1 more source

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