Results 1 to 10 of about 865,085 (290)
Systematic analysis of JmjC gene family and stress-response expression of KDM5 subfamily genes in Brassica napus [PDF]
PeerJ, 2021 Background Jumonji C (JmjC) proteins exert critical roles in plant development and stress response through the removal of lysine methylation from histones.
Xinghui He +5 more
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CircPVT1: a pivotal circular node intersecting Long Non-Coding-PVT1 and c-MYC oncogenic signals
Molecular Cancer, 2022 The role of circular RNAs in oncogenesis has begun to be widely studied in recent years, due to the significant impact that these molecules have in disease pathogenesis, as well as their potential for the future of innovative therapies.
Alina Catalina Palcau +5 more
doaj +1 more source
Nature Communications, 2021 Exposure at birth to maternal microbiota has significant effects on offspring health and development. Here, the authors validate a model where inoculation of mice at birth with human vaginal microbiota produces significant effects on offspring health ...
Eldin Jašarević +10 more
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Nature Communications, 2023 BRD4-NUT’s bipartite binding and activation of p300 in NUT carcinoma nucleates a feed-forward spread of histone hyperacetylation and chromatin condensation that sustains aberrant pro-proliferation gene transcription and perpetual tumor cell growth.
Di Yu +13 more
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Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis
Nature Communications, 2021 22G-RNAs are single-stranded antisense small RNAs that are expressed in C. elegans germline. Here the authors show that CSR-1 dependent 22G-RNAs are produced in the cytosol on mRNAs actively engaged in translation and that codon usage of an mRNA ...
Meetali Singh +8 more
doaj +1 more source
Non-mammalian model organisms in epigenetic research : an overview [PDF]
, 2020 Recent advances in sequencing technology and genome editing tools had an indisputably enormous impact on our understanding of complex biological pathways and their genetic and epigenetic regulation.
Baruah, Sri Kartik +3 more
core +2 more sources
eLife, 2017 Tumor suppressor p53 prevents cell transformation by inducing apoptosis and other responses. Homozygous TP53 deletion occurs in various types of human cancers for which no therapeutic strategies have yet been reported.
Yichao Fan +15 more
doaj +1 more source
Nature Communications, 2021 In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.
Piergiuseppe Quarato +7 more
doaj +1 more source
chroGPS, a global chromatin positioning system for the functional analysis and visualization of the epigenome [PDF]
, 2013 Development of tools to jointly visualize the genome and the epigenome remains a challenge. chroGPS is a computational approach that addresses this question.
Font-Burgada, Joan +3 more
core +1 more source
BMC Biology, 2021 An amendment to this paper has been published and can be accessed via the original article.
Léonard Hérault +5 more
doaj +1 more source