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Aging: Epigenetic modifications
2023Aging is one of the most complex and irreversible health conditions characterized by continuous decline in physical/mental activities that eventually poses an increased risk of several diseases and ultimately death. These conditions cannot be ignored by anyone but there are evidences that suggest that exercise, healthy diet and good routines may delay ...
Sarita, Mishra +4 more
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Epigenetics in ageing and development
Mechanisms of Ageing and Development, 2018The idea that a universal epigenetic program, which is reset during embryogenesis and influenced by diet and other environmental factors, can drive not only development but also ageing is gaining recognition, and embodies the idea that this is a major target for the future development of therapeutic strategies to improve health and longevity.
Gabbianelli R., Malavolta M.
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Epigenetic age oscillates during the day [PDF]
Since their introduction, epigenetic clocks have been extensively used in aging, human disease, and rejuvenation studies. In this article, we report an intriguing pattern: epigenetic age predictions display a 24-h periodicity. We tested a circadian blood
Akhil Nair
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[Epigenetics and aging: How is epigenetics linked to aging?]
Medecine sciences : M/S, 2023Links between aging and epigenetics have been revealed by bio-mathematicians. Methylation of cytosine, which is a characteristic of the epigenome, varies with age on some ADN loci, increasing or decreasing. From an analysis of the methylome, algorithms giving an "epigenetic age" were obtained, strongly correlated with the age.
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2019
The term epigenetics refers to the heritable alterations not due to changes in DNA sequences, which modulate the individual phenotype by modulating the expression and the activity of genes (Armstrong, Epigenetics, Garland Science, New York, 2013; Pinel et al., BioSocieties 13:276–303, 2018).
Bellizzi D +4 more
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The term epigenetics refers to the heritable alterations not due to changes in DNA sequences, which modulate the individual phenotype by modulating the expression and the activity of genes (Armstrong, Epigenetics, Garland Science, New York, 2013; Pinel et al., BioSocieties 13:276–303, 2018).
Bellizzi D +4 more
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2020
Epigenetics is considered as a dynamic interface between the genome and the environment and encompasses different mechanisms that regulate chromatin dynamics and gene expression by DNA methylation, histone post-translational modifications, histone variants, non-coding RNAs, genome topology, among others.
Nancy Monroy-Jaramillo +1 more
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Epigenetics is considered as a dynamic interface between the genome and the environment and encompasses different mechanisms that regulate chromatin dynamics and gene expression by DNA methylation, histone post-translational modifications, histone variants, non-coding RNAs, genome topology, among others.
Nancy Monroy-Jaramillo +1 more
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Epigenetics of Aging and Epigenetic Modifications of Aging-Associated Diseases
Aging is a complex process characterized by various biological, morphological, and anatomical changes. The epigenetic modifications include DNA methylation, histone modifications, and the action of non-coding RNA play essential roles in genes function as we age.Tejasvini Ramesh +2 more
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2010
TABLE OF CONTENTS 1. Epigenetics and the Aging Process Trygve O. Tollefsbol PART I: DNA Methylation and Histone Modifications in Aging 2. Age-related Genomic Hypomethylation Igor P. Pogribny and Boris F. Vanyushin 3. Gene-specific Hypermethylation in Aging Adebayo D. Akintola and Alan K. Parrish 4.
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TABLE OF CONTENTS 1. Epigenetics and the Aging Process Trygve O. Tollefsbol PART I: DNA Methylation and Histone Modifications in Aging 2. Age-related Genomic Hypomethylation Igor P. Pogribny and Boris F. Vanyushin 3. Gene-specific Hypermethylation in Aging Adebayo D. Akintola and Alan K. Parrish 4.
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Cancer epigenetics in clinical practice
Ca-A Cancer Journal for Clinicians, 2023Veronica Davalos, Esteller M
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