Accelerated epigenetic aging in Werner syndrome. [PDF]
Aging, 2017 Individuals suffering from Werner syndrome (WS) exhibit many clinical signs of accelerated aging. While the underlying constitutional mutation leads to accelerated rates of DNA damage, it is not yet known whether WS is also associated with an increased ...
Flunkert, Julia +5 more
core +5 more sources
Epigenetic age acceleration and clinical outcomes in gliomas.
PLoS ONE, 2020 Epigenetic age acceleration-the difference between an individual's DNA methylation age and chronological age-is associated with many diseases including cancer. This study aims to evaluate epigenetic age acceleration as a prognostic biomarker for gliomas.
Chunlei Zheng +3 more
doaj +4 more sources
Epigenetic age acceleration in peripheral blood correlates with brain-MRI age acceleration. [PDF]
BrainAbstract As the world’s population ages, more and more people are expected to suffer from age-related diseases. Biological ageing markers derived from DNA methylation and brain structure show promise in predicting health outcomes. Understanding the relationship between these biomarkers can promote the development of effective health ...
Sant'Anna Barbosa Ferreira P +5 more
europepmc +4 more sources
The Effect of Epigenetic Age Acceleration on Atopic Dermatitis: A Mendelian Randomization Study [PDF]
Clinical, Cosmetic and Investigational DermatologyYu Xin, Bingqing Dai, Jun Wang Department of Dermatology, Yijishan Hospital Affiliated with Wannan Medical College, Wuhu, Anhui, People’s Republic of ChinaCorrespondence: Jun Wang, Email 1813wj@163.comIntroduction: Atopic dermatitis (AD) is a chronic ...
Xin Y, Dai B, Wang J
doaj +2 more sources
Exposure to Violence Accelerates Epigenetic Aging in Children [PDF]
Scientific Reports, 2017 Epigenetic processes, including DNA methylation, change reliably with age across the lifespan, such that DNA methylation can be used as an “epigenetic clock”.
Tanja Jovanovic +7 more
doaj +3 more sources
Epigenetic age acceleration and allergic diseases: a bidirectional two-sample Mendelian randomization study [PDF]
Clinical EpigeneticsObjective The epigenetic clock has been regarded as a highly accurate predictor of capturing the complexity between aging and the epigenome. However, there is limited understanding of the epigenetic clock in allergic diseases.
Junfang Sun +4 more
doaj +2 more sources
Epigenetic age acceleration in hematopoietic stem cell transplantation
HaematologicaNot available.
Margherita Ursi +23 more
doaj +4 more sources
Unraveling the causal association of epigenetic age acceleration with common oral diseases and its underlying mechanisms: findings from Mendelian randomization and integrative genetic analysis [PDF]
Clinical EpigeneticsObjective The epigenetic clock is recognized as a highly accurate predictor of biological aging, but the relationship between epigenetic age acceleration and oral diseases remains poorly understood. This study aimed to investigate the causal associations
Lianjie Peng +5 more
doaj +2 more sources
Epigenetic age acceleration and rheumatoid arthritis: an NHANES-based analysis and survival prediction models [PDF]
Clinical EpigeneticsObjective Epigenetic aging has been confirmed to be associated with the pathogenesis of rheumatoid arthritis (RA), however, its role in the prognosis of RA remains unclear.
Yuhang Ou +8 more
doaj +2 more sources
Epigenetic age acceleration and mortality risk prediction in US adults. [PDF]
GeroscienceAbstractBackgroundEpigenetic clocks have emerged as novel measures of biological age and potential predictors of mortality. We aimed to test whether epigenetic age acceleration (EAA) estimated using different epigenetic clocks predict long-term overall, cardiovascular or cancer mortality.MethodsWe analyzed data from 2,105 participants to the 1999-2002 ...
Mendy A, Mersha TB.
europepmc +5 more sources