Results 241 to 250 of about 5,571,062 (272)

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Accelerated Epigenetic Aging in Children and Adults With a Fontan Circulation

JACC: Advances
Nigel E. Drury, John Stickley, Rami Dhillon, Thomas P. Gaffey, Wei Guo, Xiaojing Yang, Yap C. Chew, Paul F. Clift   +7 more
openaire   +2 more sources

Relationship stress and epigenetic age acceleration among older U.S. adults in the Midlife in the United States study. [PDF]

Epigenomics
Rodrigues M, Bather JR, Cuevas AG.
europepmc   +1 more source

The joint effects of exposure to prenatal pesticides and psychosocial factors on epigenetic age acceleration in the first 5 years of life in a South African birth cohort.

Abrishamcar S, Eick SM, Everson T, Suglia SF, Fallin MD, Wright RO, Andra SS, Chovatiya J, Jagani R, Barr DB, Lussier AA, Dunn EC, MacIsaac JL, Dever K, Kobor MS, Hoffman N, Koen N, Zar HJ, Stein DJ, Hüls A.   +19 more
europepmc   +1 more source

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Postpartum sleep loss and accelerated epigenetic aging

Sleep Health, 2021
Insufficient sleep has been linked to accelerated biological aging in adults, providing a possible mechanism through which sleep may influence disease risk. In the current paper, we test the hypothesis that short sleep in postpartum would predict older biological age in women one year post birth, as indicated by accelerated epigenetic aging.As part of ...
Judith E. Carroll, Kharah M. Ross, Steve Horvath, Michele Okun, Calvin Hobel, Kelly E. Rentscher, Mary Coussons-Read, Christine Dunkel Schetter   +7 more
openaire   +2 more sources

Effect of a 3-Week Multidisciplinary Body Weight Reduction Program on the Epigenetic Age Acceleration in Obese Adults [PDF]

Journal of Clinical Medicine, 2022
Obesity and aging share common molecular and cellular mechanisms underlying the pathophysiology of cardiovascular diseases (CVD), which occur frequently in both conditions.
Silvano Cella, Valentina Bollati, Antonello Emilio Rigamonti   +2 more
exaly   +2 more sources

Accelerated epigenetic aging in alcohol dependence

Journal of Psychiatric Research
Alcohol dependence poses a global health threat associated with aging and reduced life expectancy. Recently, aging research through deoxyribonucleic acid (DNA) methylation has gained attention. New epigenetic clocks have been developed; however, no study has investigated GrimAge components, GrimAge2 components and DunedinPACE in patients with alcohol ...
Toshiyuki Shirai, Satoshi Okazaki, Ikuo Otsuka, Masao Miyachi, Takaki Tanifuji, Ryota Shindo, Shohei Okada, Haruka Minami, Tadasu Horai, Kentaro Mouri, Akitoyo Hishimoto   +10 more
openaire   +2 more sources