Results 251 to 260 of about 5,571,062 (272)
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Increased epigenetic age acceleration in the hidradenitis suppurativa skin
Archives of Dermatological Research, 2022Epigenetic (or DNA methylation) age is calculated based on methylation of certain cytosine-guanine (CpG) repeats, and it can accurately estimate one's chronologic age. Importantly, epigenetic age acceleration (EAA) is highly predictive of age-associated morbidity and all-cause mortality.
Danitza, Lukac +5 more
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Antipsychotic Polypharmacy and Epigenetic Age Acceleration in Schizophrenia
PharmacopsychiatryAbstract Schizophrenia spectrum disorders (SSD) are debilitating psychiatric illnesses that require extensive pharmacologic, cognitive, and functional management. SSD patients are often prescribed different medications, most commonly antipsychotics, which bear ...
George, Nader +7 more
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Epigenetic Age Acceleration and Change in Frailty in MOBILIZE Boston
The Journals of Gerontology: Series A, 2022Abstract Age-associated changes in DNA methylation have been implicated as 1 mechanism to explain the development of frailty; however, previous cross-sectional studies of epigenetic age acceleration (eAA) and frailty have had inconsistent findings. Few longitudinal studies have considered the association of eAA with change in frailty. We
Benjamin J Seligman +4 more
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Map of epigenetic age acceleration: A worldwide analysis
Ageing Research ReviewsWe present a systematic analysis of epigenetic age acceleration based on by far the largest collection of publicly available DNA methylation data for healthy samples (93 datasets, 23 K samples), focusing on the geographic (25 countries) and ethnic (31 ethnicities) aspects around the world. We employed the most popular epigenetic tools for assessing age
Igor Yusipov +4 more
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Personality and cognitive resilience to accelerated epigenetic aging
Journal of Psychiatric ResearchPersonality traits are associated with cognitive resilience to dementia-related neuropathology. This study examines whether personality traits are related to cognitive resilience to accelerated epigenetic aging. Participants were adults aged from 50 to 98 years (N = 2926, 58% female, Mean age = 68.72, SD = 9.57) from the Health and Retirement Study ...
Yannick Stephan +4 more
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A case-control study: epigenetic age acceleration in psoriasis
Archives of Dermatological ResearchPsoriasis (PsO) is a chronic inflammatory skin condition, often accompanied by psoriatic arthritis (PsA) and linked to various comorbidities and increased mortality rates. This study aimed to explore the relationship between PsO and accelerated biological aging, specifically focusing on epigenetic DNA methylation clocks.
Betul Macit +8 more
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Does accelerated epigenetic ageing predict accelerated future musculoskeletal ageing?
2022The ability to predict those at risk of more rapid musculoskeletal ageing is vital if therapeutic strategies are to be successful. Precise description of the ageing musculoskeletal phenotype combined with the mapping of epigenetic changes, specifically those within the DNA methylome, enable precise age prediction and ‘epigenetic clocks’ have been ...
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Association between depression and epigenetic age acceleration: A co‐twin control study
Depression and Anxiety, 2022Chang Liu, Viola Vaccarino
exaly
Epigenetic Age Acceleration Was Delayed in Schizophrenia
Schizophrenia Bulletin, 2021Cunyou Zhao
exaly