Residential Segregation and Epigenetic Age Acceleration Among Older-Age Black and White Americans. [PDF]
DeAngelis R +5 more
europepmc +1 more source
Association of systemic immune-inflammation index (SII) with epigenetic age acceleration in adults: insights from NHANES. [PDF]
Liu R, Liu M, Wang C, Tao Z, Hu G.
europepmc +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia +4 more
wiley +1 more source
Association of blood cadmium levels with epigenetic age acceleration in U.S. adults aged > 50 years. [PDF]
Mi P, Cao X, Feng H, Wang H.
europepmc +1 more source
Progress of metabolomics‐centric multi‐omics research in medicine
The graphical abstract illustrates a holistic roadmap for metabolomics‐centric multi‐omics integration in medical research. The upper panel depicts the technological transition from traditional bulk analysis to high‐resolution single‐cell and spatial methodologies, specifically addressing inherent challenges such as molecular complexity and dynamic ...
Ziyi Wang +6 more
wiley +1 more source
Epigenetic Age Acceleration Mediates Treatment Effects on Cardiometabolic and Cardiovascular Risk in Childhood Cancer Survivors. [PDF]
Meng X +18 more
europepmc +1 more source
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
Ethnicity-specific patterns of epigenetic age acceleration in rheumatoid arthritis. [PDF]
Sharma-Oates A +9 more
europepmc +1 more source

