Results 251 to 260 of about 193,396 (281)

Epigenetic clocks, aging, and cancer

Science, 2022
Global methylation changes in aging cells affect cancer risk and tissue ...
Sarah E, Johnstone, Vadim N, Gladyshev, Martin J, Aryee, Bradley E, Bernstein   +3 more
openaire   +2 more sources

Epigenetic Clocks

Evolutionary Anthropology: Issues, News, and Reviews, 2018
AbstractRecent research has revealed clock‐like patterns of epigenetic change across the life span in humans. Models describing these epigenetic changes have been dubbed “epigenetic clocks,” and they can not only predict chronological age but also reveal biological age, which measures physiological homeostasis and deterioration over the life span ...
Elaine E. Guevara, Richard R. Lawler
openaire   +2 more sources

Epigenetic Drift, Epigenetic Clocks and Cancer Risk

Epigenomics, 2016
It is well-established that the DNA methylation landscape of normal cells undergoes a gradual modification with age, termed as 'epigenetic drift'. Here, we review the current state of knowledge of epigenetic drift and its potential role in cancer etiology.
Shijie C, Zheng, Martin, Widschwendter, Andrew E, Teschendorff   +2 more
openaire   +2 more sources

Epigenetic clock analysis in methamphetamine dependence

Psychiatry Research, 2022
Methamphetamine (MA) is used worldwide and causes serious public health and social problems. MA affects the central nervous, cardiac, and immune systems, which causes neuropsychiatric and cardiovascular diseases and infection. Epigenetic changes, including DNA methylation (DNAm), are associated with various clinical phenotypes of MA abuse.
Yukihiro Takemura, Takaki Tanifuji, Satoshi Okazaki, Yutaka Shinko, Ikuo Otsuka, Tadasu Horai, Toshiyuki Shirai, Katsuro Aso, Noriya Yamamoto, Akitoyo Hishimoto   +9 more
openaire   +2 more sources

The Epigenetic Language of Circadian Clocks

2013
Epigenetic control, which includes DNA methylation and histone modifications, leads to chromatin remodeling and regulated gene expression. Remodeling of chromatin constitutes a critical interface of transducing signals, such as light or nutrient availability, and how these are interpreted by the cell to generate permissive or silenced states for ...
Saurabh, Sahar, Paolo, Sassone-Corsi
openaire   +2 more sources

Epigenetic/circadian clocks and PCOS

Human Reproduction
Abstract Polycystic ovary syndrome (PCOS) affects 6–20% of reproductive-aged women. It is associated with increased risks of metabolic syndrome, Type 2 diabetes, cardiovascular diseases, mood disorders, endometrial cancer and non-alcoholic fatty liver disease.
Camille Vatier, Sophie Christin-Maitre
openaire   +2 more sources

Epigenetic Aging Clocks in Ecology and Evolution

Trends in Ecology & Evolution, 2019
The development of 'epigenetic clocks' is changing how biomedical scientists approach age-associated disease and leads to new insights and questions of wider significance. We highlight recent findings concerning epigenetic aging and discuss their relevance to life history evolution and their potential for advancing the field of ecological and ...
Benjamin B, Parrott, Emily M, Bertucci
openaire   +2 more sources

An epigenetic clock for kids

C&EN Global Enterprise, 2019
Epigenetic clocks use DNA methylation to measure biological age. Differences between biological age and actual chronological age can reflect health issues. Such clocks are constructed by measuring DNA methylation at multiple sites and correlating that with the known age.
openaire   +1 more source

Epigenetic clock of cell dynamics

Nature Methods, 2022
openaire   +2 more sources

Epigenetic Clocks Are Not Accelerated in COVID-19 Patients

International Journal of Molecular Sciences, 2021
Margherita Vieri, Nikolaus Marx, Yang Han   +2 more
exaly