Results 131 to 140 of about 89,797 (267)

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Re-searching nasopharyngeal carcinoma

Guangxi Yike Daxue xuebao
Nasopharyngeal carcinoma (NPC) has been a focus of medical research for more than 100 years, with significant interest emerging over the last 58 years following the identification of the link between the disease and Epstein-Barr virus (EBV) infection ...
Ingemar Ernberg, ZHENG Shixing, ZHOU Xiaoying   +2 more
doaj   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Multiomics Screening Identified CpG Sites and Genes That Mediate the Impact of Exposure to Environmental Chemicals on Cardiometabolic Traits

Epigenomes
An understanding of the molecular mechanism whereby an environmental chemical causes a disease is important for the purposes of future applications. In this study, a multiomics workflow was designed to combine several publicly available datasets in order
Majid Nikpay
doaj   +1 more source

Epigenomic regulation of heart failure: integrating histone marks, long noncoding RNAs, and chromatin architecture. [PDF]

, 2018
Epigenetic processes are known to have powerful roles in organ development across biology. It has recently been found that some of the chromatin modulatory machinery essential for proper development plays a previously unappreciated role in the ...
McKinsey, Timothy A, Vondriska, Thomas M, Wang, Yibin   +2 more
core  

Epigenetic Regulation in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
The aim of this narrative literature review was to identify epigenetic marks associated with periodontitis and to place them in a biological context. The literature was reviewed based on pre‐defined criteria. Cell type specific chromatin and mRNA modifications were included.
Henrik Dommisch, Arne Sönke Schäfer, Denica Kuzmanova, Dominique S. Michaud   +3 more
wiley   +1 more source

Beyond Deterministic Fetal Programming: Intrauterine Exposures and the Multifactorial Origins of Adiposity

Obesity Reviews, EarlyView.
ABSTRACT Excess adiposity is not a recently developed problem but has existed since at least the upper Paleolithic, allowing evolutionary selection pressures to adapt the physiology of the pregnant woman and the feto‐placental unit for maternal and fetal protection.
Gernot Desoye, Ursula Hiden, Evelyn Jantscher‐Krenn, Herbert Fluhr, Jonathan C. Wells, Sonja Entringer, Mireille N. M. van Poppel   +6 more
wiley   +1 more source

Single‐Cell CRISPR: An Efficient Strategy for Decoding Plant Cis‐Regulatory Complexity

Plant Biotechnology Journal, EarlyView.
ABSTRACT The generation of complex traits involves the coordinated interplay of multiple gene networks. Elucidating the function of transcriptional cis‐regulatory elements (CREs) in regulating gene expression is crucial for understanding complex regulatory pathways and improving our ability to modify macro‐phenotypes.
Yuanhang Zhang, Xuanxuan Luo, Hongbin Li, Shuangxia Jin, Xianlong Zhang, Maojun Wang   +5 more
wiley   +1 more source

Functional Characterisation of HAIRPLUS (NtHAP) Genes Involved in Trichome Development and Specialised Metabolism of Tobacco

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant glandular trichomes are specialised epidermal structures capable of synthesising, storing and secreting numerous varieties of secondary metabolites in different classes and are central to plant defence and the biosynthesis of high‐value metabolites.
Hai Liu, Reid Farmer, Raja Payyavula, Chengalrayan Kudithipudi, Michael P. Timko   +4 more
wiley   +1 more source

Oncogenic viruses rewire the epigenome in human cancer

Frontiers in Cellular and Infection Microbiology
Viruses contribute to approximately 15–20% of global cancer cases, yet the full spectrum of their oncogenic mechanisms continues to be uncovered. Beyond the classical roles of genome integration, chronic inflammation, and immune evasion, mounting ...
Jhommara Bautista, Jhommara Bautista, Jhommara Bautista, Andrés Lopez-Cortes   +3 more
doaj   +1 more source