Results 151 to 160 of about 30,324 (266)

Precision Rehabilitation in Spinal Cord Injury: A Systematic Review of Omics Applications for Intervention Monitoring in Spinal Cord Injury. [PDF]

Arch Rehabil Res Clin Transl
Stacul A, Valido E, Nyfeler N, Bertolo A, Zeh RM, Fontana AO, Pannek J, Krebs J, Leichtle A, Glisic M, Stoyanov J.   +10 more
europepmc   +1 more source

Parallel Liquid Biopsy Analysis of miR‐371a‐3p and Cell‐Free DNA in an Unselected Cohort of Patients With Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background Despite robust data showing strong potential to improve diagnosis and disease monitoring in testicular germ cell tumors (TGCTs), miR‐371a‐3p testing has not yet been implemented in routine clinical practice. Cell‐free DNA (cfDNA) represents another promising liquid biopsy biomarker that may provide complementary molecular ...
Laura Matouskova, Romy Kralova, Eva Parobkova, Violeta Bakardjieva‐Mihaylova, Martina Zwyrtkova, Karolina Skvarova Kramarzova, Ludmila Boublikova   +6 more
wiley   +1 more source

Epigenomics and Genomics

Cellular Oncology, 2008
doaj   +1 more source

Multiomics for Risk Stratification in Atherosclerotic Cardiovascular Disease. [PDF]

Circ Genom Precis Med
Nordestgaard LT, Magni P, Sopić M, Chemaly M, Matic L, Dalila N, Trindade F, Wolford BN, Rodriguez-Hernandez Z, Amigó N, Catapano AL, Masana L, Devaux Y.   +12 more
europepmc   +1 more source

Editorial: Advancements in sequencing technologies for epigenomic and transcriptomic analysis: from bulk to single-cell resolution. [PDF]

Front Genet
Veschetti L, Cocca M, Dago DN, Malerba G.   +3 more
europepmc   +1 more source

Virtual cell construction for artificial intelligence‐driven drug discovery

British Journal of Pharmacology, EarlyView.
Cells are the fundamental units through which genetic variation and pharmacological perturbations influence disease processes and therapeutic responses. However, cellular responses to intervention are strongly shaped by biological context, creating a central challenge for drug discovery: predicting how specific perturbations reshape cellular systems ...
Yuran Jia, Xiao Xing, Haoyang Han, Yuansong Zhao, Shiyao Zhou, Jingjing Chen   +5 more
wiley   +1 more source

Gastric Mucosal Molecular Alterations and Multimodal Field‐Based Risk Models for Gastric Cancer Development

Cancer Science, EarlyView.
DNA methylation in non‐neoplastic background gastric mucosa reflects cumulative inflammatory and exposure‐related field changes before cancer develops. Combining methylation with clinical, endoscopic, histological, and emerging multimodal information may refine calibrated gastric cancer risk prediction and support risk‐adapted personalized endoscopic ...
Genki Usui, Atsushi Kaneda
wiley   +1 more source

Learning a pairwise epigenomic and transcription factor binding association score across the human genome. [PDF]

Bioinformatics
Kwon SB, Ernst J.
europepmc   +1 more source

SERPINE1 Alternative Polyadenylation Influences Gastric Cancer Prognosis via N6‐Methyladenosine Modification

Cancer Science, EarlyView.
Multi‐omics integration of the transcriptomic APA landscape and m6A modifications identifies key prognostic genes. Their biological functions and molecular mechanisms in promoting tumor progression are comprehensively validated through in vitro assays. ABSTRACT Alternative polyadenylation (APA) and N6‐methyladenosine (m6A) methylation are critical post‐
Zhuoyi Wu, Ruyun Xu, Ju Fang, Bing Liu, Cao Zhang, Shangxin Zhang, Jing Ni   +6 more
wiley   +1 more source

The evolving role of OMICS in gastrointestinal tumor biology and clinical practice. [PDF]

Mol Cancer
Li Q, Zhang J, Chen J, Zhang Q, Liu R, Zhu J, Qing Y, Wei X, Sheng J.   +8 more
europepmc   +1 more source