Results 221 to 230 of about 52,554 (369)

Epigenomics: maternal high‐fat diet exposure in utero disrupts peripheral circadian gene expression in nonhuman primates

, 2010
Melissa Suter, Philip Bocock, Lori Showalter, Min Hu, Cynthia Shope, Robert A. McKnight, Kevin L. Grove, Robert H. Lane, Kjersti Aagaard‐Tillery   +8 more
openalex   +2 more sources

Bridging epigenomics and tumor immunometabolism: molecular mechanisms and therapeutic implications. [PDF]

Mol Cancer
Xie X, Liu W, Yuan Z, Chen H, Mao W.
europepmc   +1 more source

BRCA1 Promoter Methylation in Ovarian Cancer: Clinical Relevance and a Novel Diagnostic Approach Using Fragment Analysis

Cancer Science, EarlyView.
With the aim of clinical applications, we established a simplified evaluation method for BRCA1 methylation using fragment analysis, called BRCA1‐FAM. We confirmed that high‐grade serous ovarian cancer patients with BRCA1 methylation had poor prognosis.
Saki Tsuchimochi, Yoko Yamamoto, Ayumi Taguchi, Masahito Kawazu, Kenbun Sone, Masako Ikemura, Kana Tamai, Shuhei Kitamura, Daisuke Yoshimoto, Sayuri Fukaya, Aya Ishizaka, Anh Duong Quynh, Akira Nishijima, Yuichiro Miyamoto, Mayuyo Mori, Osamu Hiraike, Kosei Hasegawa, Tetsuo Ushiku, Katsutoshi Oda, Yasushi Hirota, Yutaka Osuga   +20 more
wiley   +1 more source

P416: DNA METHYLATION-BASED CHARACTERIZATION OF ACUTE MYELOID LEUKEMIA POINTS TOWARDS KDM3B AS A 5Q HAPLOINSUFFICIENCY CANDIDATE

HemaSphere, 2023
Katherine Kelly, Etienne Sollier, Anna Riedel, Linda Welte, Ekaterina Jahn, Hartmut Döhner, Konstanze Döhner, Pavlo Lutsik, Christoph Plass   +8 more
doaj   +1 more source

Toll-like receptor 2 deficiency induces epigenomic, transcriptomic and microbiomic changes in the colonic mucosa of mice. [PDF]

, 2011
Richárd Kellermayer, Alfred Balasa, Alan W. Harris, Tiffany D. Schaible, Scot E. Dowd, Nina Tatevian, Réka Szigeti, William Smith   +7 more
openalex   +1 more source

Transcriptomics and epigenomics datasets of primary brain cancers in formalin-fixed paraffin embedded format. [PDF]

Sci Data
García-Heredia A, Guerra-Núñez L, Martín-Climent P, Rojas E, López-Domínguez R, Alcántara-Domínguez C, Alenda C, Valor LM.   +7 more
europepmc   +1 more source

OCT‐2 Is Associated With Pro‐Metastatic Epigenomic Properties of Triple‐Negative Breast Cancer Cells

Cancer Science, EarlyView.
The transcription factor OCT‐2 (encoded by POU2F2) is involved in the formation of super‐enhancers (SEs) in triple‐negative breast cancer (TNBC) cells. Overexpression of POU2F2 enhances the metastasis of TNBC cells in mice, and their expression is highly correlated to the poor prognosis of TNBC patients. ABSTRACT Triple‐negative breast cancer (TNBC) is
Kazuki Ogikubo, Jun Nishida, Kei Takahashi‐Yamashiro, Masato Morikawa, Shogo Ehata, Tetsuro Watabe, Kohei Miyazono, Daizo Koinuma   +7 more
wiley   +1 more source

Genetic and Epigenomic Footprints of Folate [PDF]

, 2012
J. Michael Salbaum, Claudia Kappen
openalex   +1 more source

The Identification of Novel Therapeutic Biomarkers in Rheumatoid Arthritis: A Combined Bioinformatics and Integrated Multi-Omics Approach. [PDF]

Int J Mol Sci
Tariq MH, Advani D, Almansoori BM, AlSamahi ME, Aldhaheri MF, Alkaabi SE, Mousa M, Kohli N.   +7 more
europepmc   +1 more source

Role of the RAB27/SYTL Axis in Tumor Microenvironment Construction

Cancer Science, EarlyView.
This review focuses on the role of the RAB27/SYTL axis in various cancer types associated with tumor microenvironment modifications. The importance of this pathway and the potential therapeutic strategies targeting vesicle production for the treatment of cancer are also discussed.
Miwa Tanaka, Takuro Nakamura
wiley   +1 more source