ChromActivity: integrative epigenomic and functional characterization assay based annotation of regulatory activity across diverse human cell types. [PDF]
Dincer TU, Ernst J.
europepmc +1 more source
The epigenomic landscape of transposable elements across normal human development and anatomy [PDF]
Choudhary, Mayank N.K.+3 more
core +1 more source
Genetic Architecture of Immune Cell DNA Methylation in the Rhesus Macaque
ABSTRACT Genetic variation that impacts gene regulation, rather than protein function, can have strong effects on trait variation both within and between species. Epigenetic mechanisms, such as DNA methylation, are often an important intermediate link between genotype and phenotype, yet genetic effects on DNA methylation remain understudied in natural ...
Christina E. Costa+12 more
wiley +1 more source
ABSTRACT Early‐life experiences can predict the environments experienced later in life, giving individuals an opportunity to develop adaptive behaviour appropriate to a likely future environment. Epigenetic mechanisms such as DNA methylation (DNAm) have been implicated in developmental behavioural plasticity; however, studies investigating this ...
Janay A. Fox+3 more
wiley +1 more source
Integrating 5-Hydroxymethylcytosine into the Epigenomic Landscape of Human Embryonic Stem Cells
Keith E. Szulwach+13 more
openalex +2 more sources
Epigenomic enhancer variants as biomarkers for colorectal cancer [PDF]
openalex +1 more source
Three generations of epigenetic clocks in mediating the adverse effect of smoking on metabolic health. [PDF]
Yeh CY, Lin WY.
europepmc +1 more source
Exploring the untapped potential of single‐cell and spatial omics in plant biology
Summary Advances in single‐cell and spatial omics technologies have revolutionised biology by revealing the diverse molecular states of individual cells and their spatial organization within tissues. The field of plant biology has widely adopted single‐cell transcriptome and chromatin accessibility profiling and spatial transcriptomics, which extend ...
Tatsuya Nobori
wiley +1 more source
Epigenomic enhancer annotation reveals a key role for NFIX in neural stem cell quiescence [PDF]
Ben Martynoga+13 more
openalex +1 more source
Black community member perceptions and ethics recommendations on epigenomic research. [PDF]
Berrios C+8 more
europepmc +1 more source