Sketching T cell atlases in the single‐cell era: challenges and recommendations
Recent advances in single‐cell technologies have enabled the creation of T cell atlases, providing detailed maps of adaptive immunity across tissues, development and disease states. These atlases help uncover T cell diversity, functional states and disease mechanisms, aiding in the identification of therapeutic targets.
Itana Bojović+3 more
wiley +1 more source
Three generations of epigenetic clocks in mediating the adverse effect of smoking on metabolic health. [PDF]
Yeh CY, Lin WY.
europepmc +1 more source
ABSTRACT The advancement of epigenetics has highlighted DNA methylation as an intermediate‐omic influencing gene regulation and phenotypic expression. With emerging technologies enabling the large‐scale and affordable capture of methylation data, there is growing interest in integrating this information into genetic evaluation models for animal ...
Adrián López‐Catalina+3 more
wiley +1 more source
Black community member perceptions and ethics recommendations on epigenomic research. [PDF]
Berrios C+8 more
europepmc +1 more source
This review explores how artificial intelligence and machine learning predict plant behavior in response to environmental stress by modeling molecular regulatory networks of plant stress responses. Their combined application with omics methods opens new avenues in understanding the functioning of plant memory and future plant memory‐based plant ...
Judit Dobránszki+8 more
wiley +1 more source
The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin+6 more
wiley +1 more source
Epigenomic pathways from racism to preterm birth: secondary analysis of the Nulliparous Pregnancy Outcomes Study: monitoring Mothers-to-be (nuMoM2b) cohort study in the USA to examine how DNA methylation mediates the relationship between multilevel racism and preterm birth in black women: a study protocol. [PDF]
Barcelona V+7 more
europepmc +1 more source
In vitro and in vivo testing methods of epigenomic endpoints for evaluating endocrine disruptors
John M. Greally
openalex +2 more sources