Results 11 to 20 of about 113,968 (310)
A two‐sample Mendelian randomization study and mediation analysis exploring the link between cathepsins and epilepsy [PDF]
Epilepsia OpenObjective This study aims to investigate the causal relationship between cathepsins and epilepsy, using Mendelian randomization (MR) and mediation analysis.
Huaiyu Sun +7 more
doaj +2 more sources
Generalized Tonic-Clonic Seizures after Self-Limited Epilepsy with Centrotemporal Spikes: A Case Series [PDF]
Annals of Child Neurology, 2022 Purpose Patients with self-limited epilepsy with centrotemporal spikes (SLECTS) rarely experience generalized tonic-clonic seizures (GTCS) after remission, and post-remission GTCS has not been thoroughly described in earlier studies.
Hye Jin Kim +9 more
doaj +1 more source
Frontiers in Neurology, 2022 According to the latest operational 2017 ILAE classification of epileptic seizures, the generalized epileptic seizure is still conceptualized as “originating at some point within and rapidly engaging, bilaterally distributed networks.” In contrast, the ...
Thandar Aung +2 more
doaj +1 more source
Genetic generalized epilepsies [PDF]
Epilepsia, 2018 SummaryThe genetic generalized epilepsies (GGEs) are mainly genetically determined disorders. Although inheritance in most cases appears to be complex, involving multiple genes, variants of a number of genes are known to contribute. Pathogenic variants of SLC2A1 leading to autosomal‐dominant GLUT1 deficiency account for up to 1% of cases, increasing to
Saul A. Mullen, Samuel F. Berkovic
openaire +5 more sources
Correlation of sleep macrostructure parameters and idiopathic epilepsies [PDF]
Arquivos de Neuro-Psiquiatria, 2002 Sleep and epilepsy share some common mechanisms. The objective of the present investigation was to study the macrostructure of sleep in patients with idiopathic epilepsies, focal and generalized, comparing these two groups to each other and to a control ...
José Roberto Santiago Barreto +2 more
doaj +1 more source
Cerebellar output controls generalized spike-and-wave discharge occurence [PDF]
, 2015 © 2015 The Authors Annals of Neurology published by Wiley Periodicals, Inc. on behalf of American Neurological Association. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (CC BY-NC-ND 4.0)
Alva, Parimala +15 more
core +17 more sources
A natural marmoset model of genetic generalized epilepsy
Molecular Brain, 2022 Epilepsy has been extensively studied as a common neurological disease. Efforts have been made on rodent and other animal models to reveal the pathogenic mechanisms of epilepsy and develop new drugs for treatment.
Xiangyu Yang +10 more
doaj +1 more source
Febrile Seizures in Idiopathic/Genetic Generalized and Self-Limited Focal Epilepsies
Archives of Epilepsy, 2021 Objectives:Febrile seizure (FS) is the most common form of childhood seizures. Furthermore, idiopathic/generalized and focal/self-limited epilepsies present at the similar age-range. They usually have a favorable outcome.
Feray BÖLÜKBAŞI TÜMAY +4 more
doaj +1 more source
Neurobiology of Disease, 2023 Generalized epilepsy affects 24 million people globally; at least 25% of cases remain medically refractory. The thalamus, with widespread connections throughout the brain, plays a critical role in generalized epilepsy.
Britta E. Lindquist +3 more
doaj +1 more source
Frontiers in Human Neuroscience, 2022 Epilepsy types differ by pathophysiology and prognosis. Transcutaneous auricular vagus nerve stimulation (taVNS) is a non-invasive treatment option in epilepsy. Nevertheless, its mode of action and impact on different types of epilepsy are still unknown.
Randi von Wrede +10 more
doaj +1 more source