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Genetic Generalized Epilepsies

Journal of Clinical Neurophysiology, 2012
In the International League Against Epilepsy's most recent revision of classification and terminology, the term idiopathic epilepsy, previously used to describe those epilepsies whose cause was unknown, but presumed genetic, has been removed. It has been replaced by the term genetic epilepsy, only to be used to describe epilepsy in which the etiology ...
William B, Gallentine, Mohamad A, Mikati
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Is There Such a Thing as “Generalized” Epilepsy?

2014
The distinction between generalized and partial epilepsies is probably one, if not the most, pregnant assertions in modern epileptology. Both absence and generalized tonic-clonic seizures, the prototypic seizures found in generalized epilepsies, are classically seen as the result of a rapid, synchronous recruitment of neuronal networks resulting in ...
van Luijtelaar G, Behr C, AVOLI, Massimo
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Idiopathic generalized epilepsies

2012
Abstract The idiopathic generalized epilepsies (IGEs) are a spectrum of epilepsy syndromes that are characterized by seizures of generalized onset, and by known or presumed genetic etiology. These syndromes occur frequently in adults and children aged above 2 years.
Amy, Kao, Pooja M, Rao
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Generic prescribing in epilepsy

Drug and Therapeutics Bulletin, 2009
Most NHS prescriptions for medicines are written generically.1 However, there are controversies around generic prescribing in epilepsy, with many specialists believing that changing the supply of an antiepileptic risks reduced seizure control or unwanted effects.2,3 Here we review the evidence and other issues around generic prescribing of medicines ...
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Juvenile myoclonic epilepsy - a generalized epilepsy syndrome?

Acta Neurologica Scandinavica, 2005
Juvenile myoclonic epilepsy (JME) has been classified as a syndrome of idiopathic generalized epilepsy and is characterized by specific types of seizures, showing a lack of pathology using magnetic resonance imaging (MRI) and computed tomography scanning.
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Pre- and post-dormitum epilepsies: Idiopathic generalized epilepsies

Sleep Medicine, 2011
Epilepsy and sleep have a profound bidirectional influence. Idiopathic generalized epilepsy (IGE) comprises a fascinating group of syndromes that constitute nearly one-third of all epilepsies. These syndromes are genetically determined and affect otherwise normal people of both sexes and all races.
E. Zambrelli, M.P. Canevini
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Idiopathic Generalized Epilepsies Imitating Focal Epilepsies

Epilepsia, 2005
Summary:  Classification of epileptic seizures and epilepsy syndromes as either focal or generalized is a fundamental and early part in the diagnostic process and is generally fairly easily accomplished. However, in patients with idiopathic generalized epilepsies, seizure and EEG features may suggest, particularly to the unwary, the occurrence of focal
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Symptomatic Epilepsies Imitating Idiopathic Generalized Epilepsies

Epilepsia, 2005
Summary:  The diagnosis of idiopathic generalized epilepsies (IGEs) is not generally difficult if one follows the clinical and electroencephalogram (EEG) definitions of each subsyndrome that constitutes IGEs. In contrast, symptomatic epilepsies develop based on organic brain lesions and are easily diagnosed by the presence of developmental delay ...
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Ictal Patterns in Generalized Epilepsy

Journal of Clinical Neurophysiology, 1993
Ictal EEG may be of great benefit in facilitating accurate classification of the underlying seizure disorder in some patients and thus guiding further investigation and management. Ictal recordings in patients with generalized epilepsies are protean in their manifestations and yet may have considerable overlap.
I, Drury, T R, Henry
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Pharmacotherapy of idiopathic generalized epilepsies

Expert Opinion on Pharmacotherapy, 2008
Idiopathic generalized epilepsies (IGE) represent about 20% of all epilepsies, are genetically determined and comprise several subgroups of syndromes. Although complete seizure control is achievable in about 80% of patients with IGE syndromes, a substantial group remains with inadequate control and unsatisfactory long-term outcome.
CURATOLO, PAOLO   +3 more
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