Results 131 to 140 of about 43,565 (217)

Multimodal approach to characterize surgically removed epileptogenic zone from patients with focal drug‐resistant epilepsy: From operating room to wet lab

Epilepsia Open, EarlyView.
Abstract Objective We have established a comprehensive sample handling protocol designed for the multiscale assessment of epileptogenic tissue. This protocol aims to identify novel therapeutic targets and enhance the diagnosis and stratification of patients with drug‐resistant epilepsy, thereby optimizing their treatment with anti‐seizure medications ...
Jenni Kyyriäinen, Adriana Della Pietra, Mastaneh Torkamani‐Azar, Mireia Gómez‐Budia, Polina Abushik, Nataliia Novosolova, Henri Eronen, Omar Narvaez, Ekaterina Paasonen, Vera Lezhneva, Anssi Pelkonen, Liudmila Saveleva, Antti Huotarinen, Ilya Belevich, Eija Jokitalo, Kuopio Epilepsy Center Epilepsy Surgery Group, Leena Jutila, Tuomas Rauramaa, Arto Immonen, Ville Leinonen, Jussi Tohka, Olli Gröhn, Reetta Kälviäinen, Tarja Malm, Alejandra Sierra   +24 more
wiley   +1 more source

Quantitative EEG and dysautonomia in patients with temporal lobe epilepsy. [PDF]

Acta Epileptol
Gabr RM, Elkholy SH, Labib AA, Shamloul RM, Baghdadi M, ElSawy NA.   +5 more
europepmc   +1 more source

Diagnostic performance of neuroimaging modalities for epileptogenic focus localization: A systematic review

Epilepsia Open, EarlyView.
Abstract Objective Accurate localization of epileptogenic foci remains of significant importance for surgical planning in drug‐resistant epilepsy. Multiple neuroimaging modalities are available; however, their comparative diagnostic performance lacks comparative detailed synthesis.
Mustafa S. Alhasan, Mohammed Khalil, Ayman S. Alhasan, Ahmed Najjar, Yasir Hassan Elhassan, Abdullah Almaghraby, Omar Alharthi, Seham Hamoud, Muhammed Amir Essibayi, Fabricio Feltrin, Sumit Singh, James Milburn, Ahmed Y. Azzam   +12 more
wiley   +1 more source

Crucial Insights from Interictal 99mTc-ECD Brain Perfusion SPECT in Enhancing Pediatric Epilepsy Diagnosis and Management. [PDF]

World J Nucl Med
Sanisetty GSC, Narayan ML, Panda PK, Sharawat IK, S R.   +4 more
europepmc   +1 more source

Predictors of etiology and drug resistance in children with new‐onset focal seizures

Epilepsia Open, EarlyView.
Abstract Objective To examine the clinical features of new‐onset focal seizures in children and investigate clinical associations and predictors of underlying etiology and drug resistance. Methods Data were gathered from The Children's Hospital at Westmead admissions for patients aged 1 month to 18 years who presented with new‐onset focal seizures ...
Byoung Chan Lee, Russell C. Dale, Elizabeth H. Barnes, Shekeeb S. Mohammad, Sachin Gupta, Chong Wong, Deepak Gill, Kavitha Kothur   +7 more
wiley   +1 more source

Thalamic Neuromodulation: New Frontiers. [PDF]

Epilepsy Curr
Hsu J, Ali R, Air E, Englot D, Muh CR, Richardson RM, Rammo R.   +6 more
europepmc   +1 more source

sEEG‐guided responsive neurostimulation to treat neocortical epilepsy: A multicenter retrospective study of the efficacy and safety of depth electrode‐mediated neuromodulation

Epilepsia Open, EarlyView.
Abstract Objectives Pivotal trials have established the effectiveness of the Responsive Neurostimulation System (RNS® System) in treating focal epilepsy. In clinical trials, depth leads were primarily used to treat mesial temporal seizure onsets while cortical strip leads were used to treat neocortical seizure onsets.
Sina Sadeghzadeh, David A. Purger, Priya Bhanot, Noriah Johnson, Daniel A. N. Barbosa, Yuhao Huang, Jay J. Park, Ethan Schonfeld, Matthew A. Abikenari, Bhav Jain, Joshua P. Aronson, Cornelia Drees, Tiffany L. Fisher, Jason Gerrard, Tyler E. Gray, Saadi Ghatan, Kevin Hines, Barbara C. Jobst, Ioannis Karakis, Steven G. Ojemann, Imran H. Quraishi, Ahmed M. Raslan, Michael D. Sather, Christopher T. Skidmore, Jon T. Willie, Chengyuan Wu, Ji Yeoun Yoo, Kevin D. Graber, Casey H. Halpern, Vivek P. Buch, Jonathon J. Parker   +30 more
wiley   +1 more source

Glucocorticoid-Induced Tumor Necrosis Factor Receptor Ligand: Correlation and Therapeutic Potential for Cognitive Impairment in Temporal Lobe Epilepsy. [PDF]

Clin Transl Sci
Li M, Shi J, Pan X, Huang H.
europepmc   +1 more source

Centromedian nucleus targeting in the pediatric population treated with thalamic responsive neurostimulation for drug‐resistant epilepsy

Epilepsia Open, EarlyView.
Abstract The management of drug‐resistant epilepsy (DRE) in the pediatric population using neurostimulation of the centromedian (CM) nucleus of the thalamus (CMN) has been reported to be effective and safe. We present a case series of pediatric patients treated with responsive neurostimulation (RNS) and report on contact localization in relation to ...
Marian Michael Bercu, Bahram Sarvi Zargar, Kathryn E. Spykman, Gabe Heredia, Alon Y. Mogilner, Angel W. Hernandez, Sanjay E. Patra, David E. Burdette, Paul Ferrari   +8 more
wiley   +1 more source

Multimodal Imaging in Epilepsy Surgery for Personalized Neurosurgical Planning. [PDF]

J Pers Med
Fiallo Arroyo J, Leon-Rojas JE.
europepmc   +1 more source