Results 101 to 110 of about 200,055 (260)
Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong +5 more
wiley +1 more source
Philosophers and psychologists often distinguish episodic or personal memory from propositional or semantic memory. A vexed issue concerns the role, if any, of memory “impressions” or “seemings” within the latter.
Teroni, Fabrice
core +1 more source
S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu +6 more
wiley +1 more source
Tunable Switching Mechanisms in HfZrO2‐Based Tunnel Junctions for High‐Performance Synaptic Arrays
This work demonstrates hybrid switching in engineered HZO‐based FTJs, enabled by controlled interlayer design and oxygen scavenging dynamics. The combined switching mechanism produces robust multilevel conductance states in large crossbar arrays, offering a materials‐driven pathway toward scalable in‐memory computing with enhanced tunability and ...
Jiwon You +8 more
wiley +1 more source
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl +27 more
wiley +1 more source
Slow wave sleep (SWS) is highly relevant for verbal and non-verbal/spatial memory in healthy individuals, but also in people with epilepsy. However, contradictory findings exist regarding the effect of seizures on overnight memory retention, particularly
Yvonne Höller +3 more
doaj +1 more source
Decoding Naturalistic Episodic Memory with Artificial Intelligence and Brain‐Machine Interface
Episodic memory weaves together what, where, and when of experience into a personal narrative. Cutting‐edge AI models may decode this intricate process in real‐life settings, revealing how neural activity encodes naturalistic memories. By merging AI with brain–machine interfaces, researchers are edging closer to mapping and even engineering memory ...
Dong Song
wiley +1 more source
This manuscript presents the WDMS platform, an AI‐assisted, self‐powered wearable dual‐mode sensor for tele‐neurology. It integrates a contact–separation TENG insole with stretchable polyurethane optical‐fiber strain sensors to synchronously track plantar pressure and lower‐limb muscle deformation.
Tianliang Li +12 more
wiley +1 more source

