Results 121 to 130 of about 38,773 (257)

Combining growth-promoting genes leads to positive epistasis in Arabidopsis thaliana

open access: yeseLife, 2014
Several genes positively influence final leaf size in Arabidopsis when mutated or overexpressed. The connections between these growth regulators are still poorly understood although such knowledge would further contribute to understand the processes ...
Hannes Vanhaeren   +8 more
doaj   +1 more source

Epistasis and the Evolution of Antimicrobial Resistance [PDF]

open access: yesFrontiers in Microbiology, 2017
The fitness effects of a mutation can depend, sometimes dramatically, on genetic background; this phenomenon is often referred to as "epistasis." Epistasis can have important practical consequences in the context of antimicrobial resistance (AMR). For example, genetic background plays an important role in determining the costs of resistance, and hence ...
openaire   +3 more sources

Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2018
Significance Takayasu arteritis (TAK) is a systemic vasculitis with unknown etiology. We identified four unreported susceptibility genes to TAK through genome-wide association studies. We successfully fine-mapped HLA associations and showed that HLA-G is
C. Terao   +40 more
semanticscholar   +1 more source

Detection of epitasis, additive and dominance variation in rice (Oryza sativa L.) using triple test cross analysis [PDF]

open access: yesElectronic Journal of Plant Breeding, 2014
An investigation was carried out to detect the epistasis, additive and dominance components of genetic variance for yield and yield attributing traits through triple test cross analysis, involving three testers (P1, P2 and their F1) and ten lines of rice.
N.R. Koli, Chandra Prakash, R.K. Mahawar ,B.L.Kumhar and S.S.Punia
doaj  

High-Order Epistasis in Catalytic Power of Dihydrofolate Reductase Gives Rise to a Rugged Fitness Landscape in the Presence of Trimethoprim Selection

open access: yesbioRxiv, 2018
Evolutionary fitness landscapes of certain antibiotic target enzymes have been comprehensively mapped showing strong high order epistasis between mutations, but understanding these effects at the biochemical and molecular levels remained open.
Y. T. Tamer   +7 more
semanticscholar   +1 more source

Generation mean analysis of the key earliness related traits in cowpea (Vigna unguiculata (L.) Walp)

open access: yesScientific African, 2022
The nature of gene action controlling agronomic traits enables plant breeders to execute a successful crop improvement programme. To elucidate the type of gene action governing the key earliness related traits in cowpea, seven populations of the six ...
Emmanuel Yaw Owusu   +6 more
doaj  

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