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How do Early-career Biology Faculty Develop Pedagogical Content Knowledge? Exploring Variation and Longitudinal Development. [PDF]
Waugh AH, Green KE, Andrews TC.
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The simplicity of protein sequence-function relationships. [PDF]
Park Y, Metzger BPH, Thornton JW.
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Discovery and validation of SSR marker-based QTL governing fresh pod yield in dolichos bean (Lablab purpureus L. Sweet). [PDF]
Gonal B+10 more
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Addressing epistasis in the design of protein function. [PDF]
Lipsh-Sokolik R, Fleishman SJ.
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Variations and predictability of epistasis on an intragenic fitness landscape
Baheti S, Raj N, Saini S.
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Dynamics in Epistasis Analysis
IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2018Finding regulatory relationships between genes, including the direction and nature of influence between them, is a fundamental challenge in the field of molecular genetics. One classical approach to this problem is epistasis analysis. Broadly speaking, epistasis analysis infers the regulatory relationships between a pair of genes in a genetic pathway ...
Aseel Awdeh+3 more
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Epistasis in Neuropsychiatric Disorders
Trends in Genetics, 2017The contribution of epistasis to human disease remains unclear. However, several studies have now identified epistatic interactions between common variants that increase the risk of a neuropsychiatric disorder, while there is growing evidence that genetic interactions contribute to the pathogenicity of rare, multigenic copy-number variants (CNVs) that ...
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Symbolic Modeling of Epistasis
Human Heredity, 2007The workhorse of modern genetic analysis is the parametric linear model. The advantages of the linear modeling framework are many and include a mathematical understanding of the model fitting process and ease of interpretation. However, an important limitation is that linear models make assumptions about the nature of the data being modeled.
Jiang Gui+5 more
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