Results 181 to 190 of about 55,446 (204)

Discovery and validation of SSR marker-based QTL governing fresh pod yield in dolichos bean (Lablab purpureus L. Sweet). [PDF]

open access: yesSci Rep
Gonal B   +10 more
europepmc   +1 more source

Addressing epistasis in the design of protein function. [PDF]

open access: yesProc Natl Acad Sci U S A
Lipsh-Sokolik R, Fleishman SJ.
europepmc   +1 more source

Dynamics in Epistasis Analysis

IEEE/ACM Transactions on Computational Biology and Bioinformatics, 2018
Finding regulatory relationships between genes, including the direction and nature of influence between them, is a fundamental challenge in the field of molecular genetics. One classical approach to this problem is epistasis analysis. Broadly speaking, epistasis analysis infers the regulatory relationships between a pair of genes in a genetic pathway ...
Aseel Awdeh   +3 more
openaire   +3 more sources

Epistasis in Neuropsychiatric Disorders

Trends in Genetics, 2017
The contribution of epistasis to human disease remains unclear. However, several studies have now identified epistatic interactions between common variants that increase the risk of a neuropsychiatric disorder, while there is growing evidence that genetic interactions contribute to the pathogenicity of rare, multigenic copy-number variants (CNVs) that ...
openaire   +2 more sources

Symbolic Modeling of Epistasis

Human Heredity, 2007
The workhorse of modern genetic analysis is the parametric linear model. The advantages of the linear modeling framework are many and include a mathematical understanding of the model fitting process and ease of interpretation. However, an important limitation is that linear models make assumptions about the nature of the data being modeled.
Jiang Gui   +5 more
openaire   +3 more sources

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