Results 61 to 70 of about 27,549 (205)
Influence of epistasis on response to genomic selection using complete sequence data
Genetics Selection Evolution, 2017 Background The effect of epistasis on response to selection is a highly debated topic. Here, we investigated the impact of epistasis on response to sequence-based selection via genomic best linear prediction (GBLUP) in a regime of strong non-symmetrical ...
Natalia S. Forneris +3 more
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Long-Range Epistasis Mediated by Structural Change in a Model of Ligand Binding Proteins. [PDF]
PLoS ONE, 2016 Recent analyses of amino acid mutations in proteins reveal that mutations at many pairs of sites are epistatic-i.e., their effects on fitness are non-additive-the combined effect of two mutations being significantly larger or smaller than the sum of ...
Erik D Nelson, Nick V Grishin
doaj +1 more source
Evaluating Methods for Modeling Epistasis Networks with Application to Head and Neck Cancer
Cancer Informatics, 2015 Epistasis helps to explain how multiple single-nucleotide polymorphisms (SNPs) interact to cause disease. A variety of tools have been developed to detect epistasis.
Rajesh Talluri, Sanjay Shete
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Privacy-preserving decision tree for epistasis detection
Cybersecurity, 2019 The interaction between gene loci, namely epistasis, is a widespread biological genetic phenomenon. In genome-wide association studies(GWAS), epistasis detection of complex diseases is a major challenge. Although many approaches using statistics, machine
Qingfeng Chen, Xu Zhang, Ruchang Zhang
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Epigenetics, epistasis and epidemics [PDF]
Evolution, Medicine, and Public Health, 2013 Department of Microbiology, Ramon y Cajal University Hospital, Ramon y Cajal Institute for Health Research (IRYCIS), Madrid, Spain *Correspondence address. Department of Microbiology, Ramon y Cajal University Hospital, Carretera de Colmenar km 9,100. 28034 Madrid, Spain.
openaire +2 more sources
Animal Research and One Health, EarlyView.vvrr1, a small RNA, post‐transcriptionally represses the transcriptional regulator LeuO, which directly inhibits the VarS/VarA two‐component system. This triggers a Csr cascade that relieves LuxO repression, ultimately modulating exopolysaccharide production to control biofilm formation and virulence in Vibrio alginolyticus.
Theerakamol Pengsakul +6 more
wiley +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long +7 more
wiley +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Field inoculation with arbuscular mycorrhizal fungi (AMF) offers a promising route to improve sustainable agriculture and food production, yet results are often variable. We investigated the mycorrhizal growth response of maize and wheat varieties recommended for farmers and found substantial variation under greenhouse conditions.
Ido Rog +5 more
wiley +1 more source
BioData MiningPurpose Epistasis, the interaction between two or more genes, is integral to the study of genetics and is present throughout nature. Yet, it is seldom fully explored as most approaches primarily focus on single-locus effects, partly because analyzing all
Sandra Batista +8 more
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Cladistics, EarlyView.Abstract During the COVID‐19 pandemic, the need for quick public health action often conflicted with the careful methods required in phylogenetics. To explore this, we reviewed 217 SARS‐CoV‐2 studies published from January 2020 to March 2025 in 121 journals.
Omkar Marne, Denis Jacob Machado
wiley +1 more source