Results 71 to 80 of about 27,549 (205)

Genetic Parameters and Genome‐Wide Association Studies for Fertility and Reproduction Traits in U.S. Katahdin Sheep Based on the Single‐Step GBLUP Methodology

open access: yesJournal of Animal Breeding and Genetics, EarlyView.
ABSTRACT Sheep production contributes to a secure and diverse food and fibre supply in the United States, with growing ethnic diversity strengthening demand. Katahdin is a composite hair‐type sheep breed developed in the United States that has become the most popular breed in many regions of the country and the first one to have genomic selection ...
Alejandra Toro Ospina   +6 more
wiley   +1 more source

The Case | Epistasis and urolithiasis

open access: yesKidney International, 2017
A 26-year-old woman was referred for recurrent urolithiasis. The first manifestation occurred 3 years before, followed by recurrent acute episodes. She underwent one ureteral stent placement, one shock wave lithotripsy, and at last a flexible ureteroscopy that allowed to retrieve all the remaining stones.
Tabibzadeh, Nathalie   +6 more
openaire   +3 more sources

Phenotypic plasticity is broadly adaptive across an elevation gradient in the Cutleaf Monkeyflower

open access: yesNew Phytologist, EarlyView.
Leaf shape plasticity expression is variable in Mimulus laciniatus. Summary Phenotypic plasticity is a key mechanism by which organisms cope with environmental heterogeneity, but its evolutionary consequences depend on how plastic responses align with the broader adaptive landscape.
Jill M. Love, Kathleen G. Ferris
wiley   +1 more source

Ion Channel Dysfunction and Therapeutic Targeting in Salivary Gland Disorders

open access: yesOral Diseases, EarlyView.
ABSTRACT Objective Salivary gland hypofunction and xerostomia represent major clinical complications of radiation therapy, autoimmune disorders such as Sjögren's disease, and inherited epithelial ion transport defects. This review integrates current knowledge on ion channel dysfunction as a central mechanistic driver of salivary gland pathology and ...
Tarek Mohamed Abd El‐Aziz   +6 more
wiley   +1 more source

Performance analysis of novel methods for detecting epistasis

open access: yesBMC Bioinformatics, 2011
Background Epistasis is recognized fundamentally important for understanding the mechanism of disease-causing genetic variation. Though many novel methods for detecting epistasis have been proposed, few studies focus on their comparison.
Shang Junliang   +5 more
doaj   +1 more source

Structural Variations Contribute to Subspeciation and Yield Heterosis in Rice

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Yield heterosis has been extensively exploited in hybrid breeding, with intersubspecific hybrids often exhibiting the most pronounced effects. However, developing elite hybrids remains a laborious and time‐consuming process. The genetic basis of heterosis has been debated for over a century, hindered largely by the lack of high‐quality genomes.
Zhiwu Dan, Yunping Chen, Wenchao Huang
wiley   +1 more source

SimHOEPI: A resampling simulator for generating single nucleotide polymorphism data with a high‐order epistasis model

open access: yesQuantitative Biology
Epistasis is a ubiquitous phenomenon in genetics, and is considered to be one of main factors in current efforts to unveil missing heritability of complex diseases.
Yahan Li   +4 more
doaj   +1 more source

A Novel AP2/ERF Transcription Factor Controls Trichome Initiation and Fruit Development in Cucumber

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Trichomes, the hair‐like outgrowths of the plant epidermis, are critical for defence, reproduction and development. However, the underlying molecular mechanisms governing their initiation remain elusive. Here, we identified CsGL2, an AP2/ERF transcription factor, as a key integrator controlling trichome initiation and fruit development in ...
Haifan Wen   +8 more
wiley   +1 more source

Generalized Walsh Transforms and Epistasis

open access: yesBulletin of the Belgian Mathematical Society - Simon Stevin, 2006
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Iglesias, M. T.   +2 more
openaire   +4 more sources

Haplotypes and Machine Learning Improve Genomic Prediction in Brassica napus

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Genomic selection (GS) is a crop and livestock improvement method suited for predicting complex agronomical traits, while genomic prediction (GP) is the development of GS models prior to their practical use in breeding programs. One of the challenges in GP is accounting for how complex genomic interactions, such as epistasis, affect the ...
Tessa R. MacNish   +4 more
wiley   +1 more source

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