Results 11 to 20 of about 220,774 (295)
Cortactin in Epithelial–Mesenchymal Transition [PDF]
Frontiers in Cell and Developmental Biology, 2020 Cortactin, a member of the actin-binding protein family, plays an important role in cell movement involving the cytoskeleton, as cell movement mediated by cortactin may induce the epithelial–mesenchymal transition.
Rong Ji +3 more
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Epithelial–Mesenchymal Transition (EMT)
International Journal of Molecular Sciences, 2023 Epithelial–mesenchymal transition (EMT) is a cellular process involved in many physiological and pathological conditions [...]
Guidalberto Manfioletti, Monica Fedele
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Epithelial–Mesenchymal Transition (EMT) 2021
International Journal of Molecular Sciences, 2022 Epithelial–mesenchymal transition (EMT) is a transdifferentiation process wherein epithelial cells acquire characteristics typical of mesenchymal cells [...]
Guidalberto Manfioletti, Monica Fedele
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Epithelial-Mesenchymal Transition [PDF]
Cancer Research, 2008 The meeting was designed to explore the intersections of signalling networks regulating and supporting epithelial-mesenchymal (EMT) and mesenchymal-epithelial transitions (MET) in development, fibrosis, and cancer.
Zavadil, Jiri +4 more
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Epithelial-mesenchymal transition [PDF]
Journal of Cell Science, 2005 The epithelial-mesenchymal transition (EMT) is an orchestrated series of events in which cell-cell and cell-extracellular matrix (ECM) interactions are altered to release epithelial cells from the surrounding tissue, the cytoskeleton is reorganized to confer the ability to move through a three-
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Targeting epithelial–mesenchymal transition [PDF]
Journal of Molecular Medicine, 2015 The epithelial–mesenchymal transition (EMT) is a process in which epithelial cells dedifferentiate to become mesenchymal cells [1–3]. The process requires them to lose their cell polarity, to relinquish their cell–cell adhesion, and to gain migratory and invasive properties.
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Epithelial-mesenchymal transitions and hepatocarcinogenesis [PDF]
Journal of Clinical Investigation, 2010 Epithelial-mesenchymal transitions (EMTs) are believed to play a role in invasion and metastasis of many types of tumors. In this issue of the JCI, Chen et al. show that a gene that has been associated with aggressive biology in hepatocellular carcinomas initiates a molecular cascade that results in EMT.
Jou, Janice, Diehl, Anna Mae
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Biomarkers for epithelial-mesenchymal transitions [PDF]
Journal of Clinical Investigation, 2009 Somatic cells that change from one mature phenotype to another exhibit the property of plasticity. It is increasingly clear that epithelial and endothelial cells enjoy some of this plasticity, which is easily demonstrated by studying the process of epithelial-mesenchymal transition (EMT).
Zeisberg, Michael, Neilson, Eric G.
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Clinical significance of epithelial‐mesenchymal transition [PDF]
Clinical and Translational Medicine, 2014 AbstractThe concept of epithelial‐mesenchymal transition (EMT), a process where cells change their epithelial towards a mesenchymal phenotype, has gained overwhelming attention especially in the cancer research community. Thousands of scientific reports investigated changes in gene, mRNA and protein expression compatible with EMT and their possible ...
Konrad Steinestel +3 more
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Respiratory Research, 2019 Background Acute respiratory distress syndrome (ARDS) is characterized by alveolar epithelial disruption. Lipoxins (LXs), as so-called “braking signals” of inflammation, are the first mediators identified to have dual anti-inflammatory and inflammatory ...
Jing-xiang Yang +7 more
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