Results 31 to 40 of about 324,947 (241)
Beni-Suef University Journal of Basic and Applied Sciences, 2023 Background In the pathophysiology of the retina, the epithelial–mesenchymal transition and oxidative stress play key roles. To find a relationship between oxidative stress and diabetic retinopathy or proliferative retinopathy, we used an in-silico ...
Brijesh Gelat +5 more
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Expression of Tumor Assosiated and Epithelial-mesenchymal Transition Markers in 2d and 3d Cell Cultures of Mcf-7 [PDF]
, 2016 The target effects on the expression of epithelial-mesenchymal transition regulation molecules are promising for cancer therapy, including breast cancer.
Herheliuk, T. (Tetiana) +4 more
core +2 more sources
Multistability in the epithelial-mesenchymal transition network [PDF]
BMC Bioinformatics, 2019 Abstract Background: The transitions between epithelial (E) and mesenchymal (M) cell phenotypes are essential in many biological processes like tissue development and cancer metastasis. previous studies, both modeling and experimental, suggested that in addition to E and M states, the network responsible for these phenotypes exhibits ...
Ying Xin, Bree Cummins, Tomáš Gedeon
openaire +4 more sources
Particle and Fibre Toxicology, 2023 Chronic exposure to silica can lead to silicosis, one of the most serious occupational lung diseases worldwide, for which there is a lack of effective therapeutic drugs and tools.
Shaoqi Yang +10 more
doaj +1 more source
A systematic approach identifies FOXA1 as a key factor in the loss of epithelial traits during the epithelial-to-mesenchymal transition in lung cancer [PDF]
, 2013 Background: The epithelial-to-mesenchymal transition is an important mechanism in cancer metastasis. Although transcription factors including SNAIL, SLUG, and TWIST1 regulate the epithelial-to-mesenchymal transition, other unknown transcription factors ...
Fei, Teng +5 more
core +1 more source
EMT and MET: necessary or permissive for metastasis? [PDF]
, 2017 Epithelial-to-mesenchymal transition (EMT) and its reverse mesenchymal-to-epithelial transition (MET) have been suggested to play crucial roles in metastatic dissemination of carcinomas. These phenotypic transitions between states are not binary. Instead,
Gilja, Shivee +4 more
core +1 more source
Molecular mechanisms controlling the phenotype and the EMT/MET dynamics of hepatocyte [PDF]
, 2014 The complex spatial and paracrine relationships between the various liver histotypes are essential for proper functioning of the hepatic parenchymal cells.
Fausto N +6 more
core +3 more sources
Epithelial-Mesenchymal Transitions [PDF]
Cell, 2004 Epithelial-mesenchymal transitions (EMT) are vital for morphogenesis during embryonic development and are also implicated in the conversion of early stage tumors into invasive malignancies. Several key inducers of EMT are transcription factors that repress E-cadherin expression.
Yibin Kang, Joan Massagué
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RGO: Revista Gaúcha de Odontologia, 2022 Objective: Odontogenic keratocysts have a high recurrence rate and aggressive clinical behavior. The event called epithelial-mesenchymal transition is a process in which the epithelial cell loses its epithelial characteristics and acquires properties ...
Joana Leticia VENDRUSCOLO +4 more
doaj +1 more source
Epithelial-Mesenchymal Transition in tumor microenvironment [PDF]
Cell & Bioscience, 2011 Abstract The epithelial to mesenchymal transition (EMT) plays crucial roles in the formation of the body plan and also in the tumor invasion process. In addition, EMT also causes disruption of cell-cell adherence, loss of apico-basal polarity, matrix remodeling, increased motility and invasiveness in promoting tumor metastasis.
Yingying Jing +4 more
openaire +4 more sources