Results 81 to 90 of about 220,774 (295)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Expression and pathogenesis of insulin-like growth factor-1 and insulin-like growth factor binding protein 3 in a mouse model of ulcerative colitis

Heliyon
Background and aim: Insulin-like growth factor-1 may be involved in the epithelial-to-mesenchymal transition process. It can mitigate adverse effects when interacting with insulin-like growth factor binding protein 3.
Weihua Wang, Xuemei Sun, Aina Wang, Yanyan Lu, Yue Han, Jianjian Zhao, Fuguo Liu, Zibin Tian   +7 more
doaj   +1 more source

Sequential Salinomycin Treatment Results in Resistance Formation through Clonal Selection of Epithelial-Like Tumor Cells

Translational Oncology, 2014
Acquiring therapy resistance is one of the major obstacles in the treatment of patients with cancer. The discovery of the cancer stem cell (CSC)–specific drug salinomycin raised hope for improved treatment options by targeting therapy-refractory CSCs and
Florian Kopp, Adam Hermawan, Prajakta Shirish Oak, Vijay Kumar Ulaganathan, Annika Herrmann, Nefertiti Elnikhely, Chitra Thakur, Zhiguang Xiao, Pjotr Knyazev, Beyhan Ataseven, Rajkumar Savai, Ernst Wagner, Andreas Roidl   +12 more
doaj   +1 more source

Supplemental Figures and Tables from Notch4 Signaling Induces a Mesenchymal–Epithelial–like Transition in Melanoma Cells to Suppress Malignant Behaviors

, 2023
Ehsan Bonyadi Rad, Heinz Hammerlindl, Christian Wels, Ulrich Popper, Dinoop Ravindran Menon, Heimo Breiteneder, Melitta Kitzwoegerer, Christine Häfner, Meenhard Herlyn, Helmut Bergler, Helmut Schaider   +10 more
openalex   +1 more source

Exosome and epithelial–mesenchymal transition: A complex secret of cancer progression [PDF]

, 2023
Rajib Dhar, Arikketh Devi, Sukhamoy Gorai, Saurabh Kumar Jha, Αθανάσιος Αλεξίου, Marios Papadakis   +5 more
openalex   +1 more source

Epithelial-mesenchymal transition in liver fibrosis

Biomedical Reports, 2016
Liver fibrosis is the result of a sustained wound healing response to sustained chronic liver injury, which includes viral, alcoholic and autoimmune hepatitis. Hepatic regeneration is the dominant outcome of liver damage. The outcomes of successful repair are the replacement of dead epithelial cells with healthy epithelial cells, and reconstruction of ...
Ya-Lei, Zhao, Rong-Tao, Zhu, Yu-Ling, Sun   +2 more
openaire   +3 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Patterning the Void: Combining L‐Systems with Archimedean Tessellations as a Perspective for Tissue Engineering Scaffolds

Advanced Functional Materials, EarlyView.
This study introduces a novel multi‐scale scaffold design using L‐fractals arranged in Archimedean tessellations for tissue regeneration. Despite similar porosity, tiles display vastly different tensile responses (1–100 MPa) and deformation modes. In vitro experiments with hMSCs show geometry‐dependent growth and activity. Over 55 000 tile combinations
Maria Kalogeropoulou, Kenny A. van Kampen, Pierpaolo Fucile, Carlos Mota, Lorenzo Moroni   +4 more
wiley   +1 more source

Epithelial–mesenchymal transition in pulmonary carcinosarcoma: case report and literature review

Therapeutic Advances in Medical Oncology, 2012
Pulmonary carcinosarcoma is a rare and aggressive neoplasm that has both epithelial and mesenchymal components. We report on a 63-year-old woman who was found to have a right upper-lobe pulmonary carcinosarcoma with metastases to the liver and gastric ...
Vibha T. Thomas, Stacy Hinson, Kartik Konduri   +2 more
doaj   +1 more source

Epithelial-mesenchymal transition: Understanding the basic concept

Journal of Orofacial Sciences, 2012
The epithelial-mesenchymal transition (EMT) is described as a rapid and reversible process of change of cell phenotype seen during embryonic development, organ fibrosis, and tumor progression.
Suresh Babu Ghanta, Neha Nayan, N Govind Raj Kumar, Swetha Pasupuleti   +3 more
doaj   +1 more source